MicroRNAs and target molecules in bladder cancer.

Medical Oncology
Payam Kheirmand PariziSeyed-Alireza Esmaeili

Abstract

Bladder cancer (BC) is considered as one of the most common malignant tumors in humans with complex pathogenesis including gene expression variation, protein degradation, and changes in signaling pathways. Many studies on involved miRNAs in BC have demonstrated that they could be used as potential biomarkers in the prognosis, response to treatment, and screening before the cancerous phenotype onset. MicroRNAs (miRNAs) regulate many cellular processes through their different effects on special targets along with modifying signaling pathways, apoptosis, cell growth, and differentiation. The diverse expression of miRNAs in cancerous tissues could mediate procedures leading to the oncogenic or suppressor behavior of certain genes in cancer cells. Since a specific miRNA may have multiple targets, an mRNA could also be regulated by multiple miRNAs which further demonstrates the actual role of miRNAs in cancer. In addition, miRNAs can be utilized as biomarkers in some cancers that cannot be screened in the early stages. Hence, finding blood, urine, or tissue miRNA biomarkers by novel or routine gene expression method could be an essential step in the prognosis and control of cancer. In the present review, we have thoroughly evaluated ...Continue Reading

References

Nov 16, 2002·Proceedings of the National Academy of Sciences of the United States of America·George Adrian CalinCarlo M Croce
Oct 22, 2003·Cell·Anastasia KhvorovaSumedha D Jayasena
Aug 16, 2005·Current Opinion in Genetics & Development·Eric A Miska
Aug 20, 2005·Nature Reviews. Cancer·Xue-Ru Wu
May 3, 2006·Biological & Pharmaceutical Bulletin·Yukihiro AkaoTomoki Naoe
Oct 31, 2006·Oncogene·M-L SiY-Y Mo
Dec 15, 2007·Genes & Development·Ingrid IbarraGregory J Hannon
Aug 23, 2008·Cell Cycle·Dmitri LodyginHeiko Hermeking
May 29, 2009·International Urology and Nephrology·Gang WangCaigan Du
Feb 17, 2010·BMC Systems Biology·An-Yuan GuoZhongming Zhao
Jun 16, 2010·International Journal of Cancer. Journal International Du Cancer·Li HuangTianxin Lin
Feb 8, 2011·European Urology·James W F CattoTapio Visakorpi
Feb 10, 2011·British Journal of Cancer·H YoshinoM Nakagawa
Mar 15, 2011·Urologic Oncology·Yousuke UchidaMasayuki Nakagawa
Apr 22, 2011·Proceedings of the National Academy of Sciences of the United States of America·Ihn Kyung JangYongrui Zou
Nov 24, 2011·British Journal of Cancer·S B VilladsenJ Kjems
Dec 14, 2011·Nature Reviews. Urology·George J Netto
Dec 20, 2011·International Journal of Oncology·Shuichi TataranoMasayuki Nakagawa
Jan 20, 2012·Bioorganic & Medicinal Chemistry Letters·Mohitosh MaitiPiet Herdewijn
Mar 6, 2012·Clinical Genitourinary Cancer·Gang WangChi-Fai Ng
May 31, 2012·British Journal of Cancer·S MiahJ W F Catto
Jun 12, 2012·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Chao ZhangXu Zhang
Aug 7, 2012·Urologic Oncology·Liana AdamColin P N Dinney
Sep 11, 2012·International Journal of Oncology·Seok Joong YunWun-Jae Kim
Dec 25, 2012·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Qin Li, Guillermina Lozano
Dec 26, 2012·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Bruno VincenziGiuseppe Tonini
Jan 15, 2013·Frontiers in Genetics·Anastasia A ZabolotnevaAnton A Buzdin
Feb 5, 2013·Briefings in Bioinformatics·Jakob Lewin RukovNoam Shomron
Apr 27, 2013·Biochemical and Biophysical Research Communications·Zhenghui HuLiping Xie

❮ Previous
Next ❯

Citations

Apr 4, 2021·Journal of Personalized Medicine·Matteo FerroDaniela Terracciano

❮ Previous
Next ❯

Related Concepts

Related Feeds

Apoptosis in Cancer

Apoptosis is an important mechanism in cancer. By evading apoptosis, tumors can continue to grow without regulation and metastasize systemically. Many therapies are evaluating the use of pro-apoptotic activation to eliminate cancer growth. Here is the latest research on apoptosis in cancer.

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

Related Papers

Histology and Histopathology
Zina Jeyapalan Rutnam, Burton B Yang
Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
F AsghariT Kazemi
Journal of Cellular Physiology
Homa MollaeiZeinab Rostami
Cell Cycle
Xu-Bao ShiRalph W deVere White
Critical Reviews in Eukaryotic Gene Expression
Muhammad Imran Qadir, Arooj Faheem
© 2021 Meta ULC. All rights reserved