May 4, 2006

MicroRNAS and their regulatory roles in plants

Annual Review of Plant Biology
Matthew W Jones-RhoadesBonnie Bartel

Abstract

MicroRNAs (miRNAs) are small, endogenous RNAs that regulate gene expression in plants and animals. In plants, these approximately 21-nucleotide RNAs are processed from stem-loop regions of long primary transcripts by a Dicer-like enzyme and are loaded into silencing complexes, where they generally direct cleavage of complementary mRNAs. Although plant miRNAs have some conserved functions extending beyond development, the importance of miRNA-directed gene regulation during plant development is now particularly clear. Identified in plants less than four years ago, miRNAs are already known to play numerous crucial roles at each major stage of development-typically at the cores of gene regulatory networks, targeting genes that are themselves regulators, such as those encoding transcription factors and F-box proteins.

Mentioned in this Paper

Complex (molecular entity)
RNA, Small Temporal
Cytokinesis of the Fertilized Ovum
Gene Expression
F-Box Domain
Plant Development
Nucleotides
Cytokinesis
Gene Regulatory Networks
DICER1 gene

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