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microRNAs as novel regulators of stem cell pluripotency and somatic cell reprogramming

BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology

Jun 8, 2012

Meng Amy Li, Lin He

Abstract

Emerging evidence suggests that microRNA (miRNA)-mediated post-transcriptional gene regulation plays an essential role in modulating embryonic stem (ES) cell pluripotency maintenance, differentiation, and reprogramming of somatic cells to an ES cell-like state. Investigations from ES ce...read more

Mentioned in this Paper

Embryo
Pluripotent Stem Cells
Cosuppression
Transcription, Genetic
RNA, Small Temporal
Signal Transduction Pathways
Cell Differentiation Process
Epithelial to Mesenchymal Transition
Study of Epigenetics
Neoplasms, Germ Cell and Embryonal
5
2
127
Paper Details
References
  • References81
  • Citations34
  • References81
  • Citations34
1234

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microRNAs as novel regulators of stem cell pluripotency and somatic cell reprogramming

BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology

Jun 8, 2012

Meng Amy Li, Lin He

PMID: 22674461

DOI: 10.1002/bies.201200019

Abstract

Emerging evidence suggests that microRNA (miRNA)-mediated post-transcriptional gene regulation plays an essential role in modulating embryonic stem (ES) cell pluripotency maintenance, differentiation, and reprogramming of somatic cells to an ES cell-like state. Investigations from ES ce...read more

Mentioned in this Paper

Embryo
Pluripotent Stem Cells
Cosuppression
Transcription, Genetic
RNA, Small Temporal
Signal Transduction Pathways
Cell Differentiation Process
Epithelial to Mesenchymal Transition
Study of Epigenetics
Neoplasms, Germ Cell and Embryonal
5
2
127

Similar Papers Found In These Feeds

Paper Details
References
  • References81
  • Citations34
  • References81
  • Citations34
1234
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