Microsaccade-rhythmic modulation of neural synchronization and coding within and across cortical areas V1 and V2

PLoS Biology
Eric LowetJan van der Eerden

Abstract

Primates sample their visual environment actively through saccades and microsaccades (MSs). Saccadic eye movements not only modulate neural spike rates but might also affect temporal correlations (synchrony) among neurons. Neural synchrony plays a role in neural coding and modulates information transfer between cortical areas. The question arises of how eye movements shape neural synchrony within and across cortical areas and how it affects visual processing. Through local field recordings in macaque early visual cortex while monitoring eye position and through neural network simulations, we find 2 distinct synchrony regimes in early visual cortex that are embedded in a 3- to 4-Hz MS-related rhythm during visual fixation. In the period shortly after an MS ("transient period"), synchrony was high within and between cortical areas. In the subsequent period ("sustained period"), overall synchrony dropped and became selective to stimulus properties. Only mutually connected neurons with similar stimulus responses exhibited sustained narrow-band gamma synchrony (25-80 Hz), both within and across cortical areas. Recordings in macaque V1 and V2 matched the model predictions. Furthermore, our modeling provides predictions on how (micro)...Continue Reading

References

Aug 22, 1989·The Journal of Comparative Neurology·A Schüz, G Palm
Feb 1, 1985·Documenta Ophthalmologica. Advances in Ophthalmology·J P PijnL H van der Tweel
Dec 1, 1966·Electroencephalography and Clinical Neurophysiology·K GaarderW Kropfl
Apr 1, 1972·The Journal of Physiology·F W Campbell, J J Kulikowski
Jan 1, 1982·Vision Research·M J Musselwhite, D A Jeffreys
Jan 1, 1995·Annual Review of Neuroscience·R Desimone, J Duncan
Jan 1, 1995·Annual Review of Neuroscience·W Singer, C M Gray
Jun 1, 1996·The Journal of Physiology·R D TraubJ G Jefferys
Apr 18, 1998·Journal of Neurophysiology·D Lee, J G Malpeli
Oct 17, 1998·Experimental Brain Research·S ChakrabortyS Lehmkuhle
Dec 22, 1998·Experimental Brain Research·D A Leopold, N K Logothetis
Jan 5, 2000·Human Brain Mapping·J P LachauxF J Varela
Mar 4, 2000·Proceedings of the National Academy of Sciences of the United States of America·N KopellR D Traub
Nov 14, 2000·Trends in Neurosciences·V A Lamme, P R Roelfsema
Oct 23, 2001·Neural Networks : the Official Journal of the International Neural Network Society·S ThorpeR Van Rullen
Jul 20, 2002·Journal of Cognitive Neuroscience·Pieter R RoelfsemaHolger Bosch
Oct 4, 2002·Proceedings of the National Academy of Sciences of the United States of America·Susana Martinez-CondeDavid H Hubel
Nov 9, 2002·Journal of Neurophysiology·James R CavanaughJ Anthony Movshon
Nov 26, 2002·Vision Research·Ziad M Hafed, James J Clark
Jan 25, 2003·Experimental Gerontology·Bente PakkenbergLisbeth Regeur
Apr 5, 2003·Vision Research·Ralf Engbert, Reinhold Kliegl
Dec 11, 1964·Science·K GAARDERJ C ARMINGTON
Feb 21, 2004·Nature Reviews. Neuroscience·Susana Martinez-CondeDavid H Hubel
Apr 6, 2004·Brain Research. Cognitive Brain Research·Wolfgang KlimeschPaul Sauseng
Aug 24, 2004·Nature Neuroscience·Pieter R RoelfsemaHenk Spekreijse
Apr 26, 2005·Neuron·Ben J A Palanca, Gregory C DeAngelis
May 20, 2005·Journal of Neurophysiology·Peter LakatosCharles E Schroeder
Oct 11, 2005·NeuroImage·Wolfgang KlimeschWalter R Gruber
Nov 9, 2005·Journal of Physiology, Paris·Rudy GuyonneauSimon J Thorpe
Dec 13, 2005·Chemical Senses·Adam KepecsZachary F Mainen
Jan 21, 2006·Neuron·Susana Martinez-CondeThomas A Dyar
Apr 25, 2006·NeuroImage·Olivier DavidKarl J Friston
Jun 17, 2006·Science·Randy M Bruno, Bert Sakmann
Jul 14, 2006·Current Opinion in Neurobiology·David KleinfeldMathew E Diamond

❮ Previous
Next ❯

Citations

Jun 19, 2019·Journal of Cognitive Neuroscience·Alessandro BenedettoAlice Tomassini
Aug 28, 2019·The European Journal of Neuroscience·Matías CavelliPablo Torterolo
Apr 4, 2019·Cerebral Cortex·Mark J RobertsPeter De Weerd
Sep 14, 2019·Annual Review of Psychology·Ian C Fiebelkorn, Sabine Kastner
Aug 10, 2019·Frontiers in Integrative Neuroscience·Marcin Leszczynski, Charles E Schroeder
Jun 30, 2021·Seminars in Pediatric Neurology·Meredith J McCarty, Audrey C Brumback
Aug 17, 2021·Frontiers in Systems Neuroscience·Kris EversMario Senden

❮ Previous
Next ❯

Related Concepts

Related Feeds

Barrel cortex

Here is the latest research on barrel cortex, a region of somatosensory and motor corticies in the brain, which are used by animals that rely on whiskers for world exploration.