Microscopic and molecular evidence in support of rodent as a reservoir for dissemination of Leishmaniasis.

Microscopy Research and Technique
Imran KhanMubashir Hussain

Abstract

Leishmaniasis is a worldwide public health problem and vector-borne disease. It is caused by a diverse group of protozoan parasites that belong to the genus Leishmania and transmitted to humans through a bite of an infected female sand fly. Leishmaniasis has attained epidemic proportion in Khyber Pakhtunkhwa and raises serious concern over its management. The present research work was conducted in cutaneous leishmaniasis (CL) prevalent village named Surgul of district Kohat, Khyber Pakhtunkhwa with a focus to investigate whether rodent can act as a source for dissemination of leishmanial species or not. In this context, rodent samples were analyzed via morphological and molecular approaches to unveil prevalence of CL. It was reported that 12.5% of samples were positive for signs of leishmaniasis through microscopy and 18.75% through polymerase chain reaction (PCR). Supporting the findings further, the color character of rodents was also taken into consideration, which shows that light dark colored rodents were more infected (13.3%) compared to brown colored rodents (11.43%). Based on our findings, we speculate that small rodents are a possible reservoir of various leishmanial parasites and play a significant role in zoonosis an...Continue Reading

References

Dec 1, 1987·Biochemical Medicine and Metabolic Biology·H S ThatteC F Louis
Jan 1, 1984·Transactions of the Royal Society of Tropical Medicine and Hygiene·Y SchleinA E Gunders
Sep 1, 1996·Clinics in Dermatology·R W Ashford
Mar 24, 1998·Transactions of the Royal Society of Tropical Medicine and Hygiene·A TayehS Cairncross
Aug 26, 1998·Emerging Infectious Diseases·F A Murphy
Dec 23, 1998·Transactions of the Royal Society of Tropical Medicine and Hygiene·S HewittM Rowland
Dec 29, 1998·Emerging Infectious Diseases·J N Mills, J E Childs
Dec 13, 2000·International Journal for Parasitology·R W Ashford
Dec 13, 2000·International Journal for Parasitology·J A PatzA Y Vittor
May 16, 2001·Science·M E WoolhouseD T Haydon
Aug 28, 2003·Medical and Veterinary Entomology·J SádlováP Volf
Jun 3, 1958·Annals of the New York Academy of Sciences·N B McCULLOUGH
Oct 31, 2003·Transactions of the Royal Society of Tropical Medicine and Hygiene·Hugh ReyburnClive Davies
Jul 1, 2004·Comparative Immunology, Microbiology and Infectious Diseases·P Desjeux
Apr 20, 2005·Emerging Infectious Diseases·Richard ReithingerSamad Hami
Sep 16, 2005·International Journal for Parasitology·Marina Gramiccia, Luigi Gradoni
Apr 11, 2008·Clinical Microbiology Reviews·Jorge AlvarJavier Moreno
Oct 30, 2008·PLoS Neglected Tropical Diseases·Caryn BernJorge Alvar
Oct 30, 2008·PLoS Neglected Tropical Diseases·Masoom KassiPashtoon Murtaza Kasi
Jul 25, 2009·Tropical Medicine & International Health : TM & IH·Francine PratlongJean-Pierre Dedet
May 5, 2010·The American Journal of Tropical Medicine and Hygiene·Dalit Talmi-FrankGad Baneth
Dec 3, 2010·Emerging Infectious Diseases·Dalit Talmi-FrankGad Baneth
Jun 14, 2012·PloS One·Jorge AlvarUNKNOWN WHO Leishmaniasis Control Team

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of the American Academy of Dermatology
S A Grevelink, E A Lerner
International Immunopharmacology
Rajeev Nagill, Sukhbir Kaur
The Journal of Investigative Dermatology. Symposium Proceedings
C M Choi, E A Lerner
Infectious Disease Clinics of North America
Alan J Magill
© 2021 Meta ULC. All rights reserved