Microscopic colitis in routine colonoscopies

Digestive Diseases and Sciences
Kaz JaskiewiczMarian Smoczyński

Abstract

Lymphocytic colitis (LC) and collagenous colitis (CC), both known as microscopic colitis (MC), are uncommon entities with increasing incidence as more clinicians take biopsies from macroscopically normal colons and as pathologists use more rigorous diagnostic criteria to be confident of the diagnosis. Information on the incidence of this type of colitis is limited and based on reported cases. The purpose of this work is to estimate the incidence of LC and CC in reviewed routine colonoscopies. We reviewed 2815 colonoscopies performed at a tertiary referral center with an open-access service using restricted histological criteria in order to establish the frequency rate of LC and CC in routine colonoscopic biopsy material. Cases suspicious for MC were stained with Masson's trichrome or Congo red stain and immunohistochemically for lymphocytes, where appropriate. Review of routine colonoscopic biopsies showed that MC is underreported in our colonoscopic material. Incidence rates of LC and CC (0.9 and 0.4, respectively) were based on morphological assessment of colonoscopic biopsies using stringent criteria together with clinical data and after differentiation with other lesions which can mimic MC. The 10.2% rate of this type of co...Continue Reading

References

Aug 1, 1991·Digestive Diseases and Sciences·K JaskiewiczH D Louwrens
May 1, 1995·Mayo Clinic Proceedings·B J ZinsH A Carpenter
Jun 1, 1993·Digestive Diseases and Sciences·L R MillsW O Thompson
Aug 1, 1996·Histopathology·A Jawhari, I C Talbot
Apr 25, 2000·Journal of Clinical Gastroenterology·W J Tremaine
Dec 23, 2000·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·J BohrG Järnerot
Mar 14, 2001·Journal of Clinical Gastroenterology·C A MatteoniE E Soffer
Apr 25, 2001·Journal of Clinical Gastroenterology·C S PokornyC J Henderson
May 31, 2001·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·A A AbdoL S Halparin

❮ Previous
Next ❯

Citations

Mar 21, 2012·International Journal of Colorectal Disease·Hong-Xiang GuYa-Li Zhang
Jan 12, 2008·World Journal of Gastroenterology : WJG·Jan Józefczuk, Bogdan Marian Wozniewicz
Dec 1, 2008·Journal of Crohn's & Colitis·Fernando Fernández-BañaresMaria Esteve
Apr 30, 2011·World Journal of Gastroenterology : WJG·Nooroudien MohamedJuanita Bezuidenhout
Aug 29, 2009·European Journal of Internal Medicine·P JobseR J L F Loffeld
Jan 21, 2009·Gastrointestinal Endoscopy·Gilberto CoutoLeopoldo Matos
Jun 19, 2013·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Amir ArdeshirDallas M Hyde
Mar 22, 2016·Gastroenterología y hepatología·Yamile ZabanaFernando Fernández-Bañares
Nov 2, 2015·Journal of Crohn's & Colitis·Julie RasmussenLars Kristian Munck
Nov 26, 2015·Alimentary Pharmacology & Therapeutics·F Fernández-BañaresUNKNOWN Spanish Microscopic Colitis Group (SMCG)
Aug 21, 2021·United European Gastroenterology Journal·Andreas MünchLars Kristian Munck

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.