PMID: 9423223Jan 10, 1998Paper

Microscopic polyarteritis following a suppurative wound infection

Pathology
P BranleyP Miach

Abstract

Bacterial and viral infections may be associated with the onset of a number of autoimmune diseases and relapses of these conditions. We describe a patient in whom there was a close temporal relationship between a suppurative wound infection and the onset of microscopic polyarteritis. The clinical features of this disease responded to treatment with high dose prednisolone and cyclophosphamide. The patient had several further infective episodes while being treated, but there were no disease exacerbations or relapses related to these. Anti-neutrophil cytoplasmic antibodies (ANCA) were never demonstrated in this patient. Thus while it is likely that the infection precipitated the onset of the systemic vasculitic illness, this occurred independently of ANCA.

References

Feb 1, 1992·Australian and New Zealand Journal of Medicine·P K LiK N Lai
Jan 1, 1991·Nephron·A Davenport, P J Grant
Apr 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·R H Scofield, J B Harley

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