PMID: 11320030Apr 26, 2001Paper

Microsporidial keratoconjunctivitis in a healthy contact lens wearer without human immunodeficiency virus infection

Ophthalmology
J ThengDonald T H Tan

Abstract

To present a rare case of microsporidial keratoconjunctivitis in an otherwise healthy contact lens wearer without human immunodeficiency virus infection who responded to treatment with systemic albendazole and topical fumagillin. Interventional case report. A cornea epithelial scraping from a man with unilateral keratoconjunctivitis previously treated with topical steroids was evaluated by modified trichome staining. The patient was evaluated for his symptoms, visual acuity, clinical observations, and pathologic examination of corneal scrapes. Modified trichome staining of an epithelial corneal scraping revealed pinkish to red organisms characteristic of microsporidia. Results of a human immunodeficiency virus (HIV) enzyme-linked immunosorbent assay test were negative. The symptoms of ocular discomfort and clinical signs of keratoconjunctivitis resolved after 2 months of treatment with albendazole and topical fumagillin. Ocular infection with microsporidia, although classically occurring in patients with HIV infection, may occur rarely in healthy individuals, especially if previously treated with systemic immune suppression or topical steroids. Microsporidial keratoconjunctivitis should be considered in the differential diagnos...Continue Reading

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Citations

Oct 1, 2003·American Journal of Ophthalmology·M S Sridhar, Savitri Sharma
Jul 18, 2003·Ophthalmology·Cordelia M L ChanDonald T H Tan
Nov 29, 2005·Eye·R KakraniaS Sharma
Aug 2, 2007·Cornea·Mandeep S SagooStephen J Tuft
Jul 16, 2005·Clinical Microbiology Reviews·Alexander MathisPeter Deplazes
Nov 26, 2011·Journal of Clinical Microbiology·Nai-Wen FanPei-Yu Lin
Jun 24, 2006·BMC Clinical Pathology·Joveeta JosephSavitri Sharma
Apr 18, 2008·Indian Journal of Ophthalmology·Nikhil S Gokhale
Aug 13, 2010·Gastroentérologie Clinique Et Biologique·S Anane, H Attouchi
Jun 19, 2007·Survey of Ophthalmology·Bennie H JengDavid M Meisler
Oct 19, 2011·Clinical & Experimental Ophthalmology·Alex Chengyao Tham, Srinivasan Sanjay
Aug 21, 2013·Transplant Infectious Disease : an Official Journal of the Transplantation Society·A NagpalM P Wilhelm
Nov 18, 2005·The Journal of Infection·Lalida Pariyakanok, Somchai Jongwutiwes
Aug 25, 2007·Annals of Tropical Medicine and Parasitology·M NorhayatiA R Rozlida
Feb 24, 2017·The British Journal of Ophthalmology·Rohan AgashePrajna Lalitha
Apr 26, 2018·The American Journal of Tropical Medicine and Hygiene·Jordan LeroyBoualem Sendid
Aug 28, 2018·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Eunice Stella Jardim CuryElenir Rose Jardim Cury Pontes
Jul 24, 2004·Journal of Medical Microbiology·Saaeha RauzAlan Curry
Dec 25, 2019·Current Eye Research·Pranita SahayJeewan S Titiyal
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Nov 23, 2019·Animals : an Open Access Journal From MDPI·Edita JeklováMartin Faldyna
Jul 1, 2021·Clinical Microbiology Reviews·Bing HanLouis M Weiss
Aug 23, 2021·The Ocular Surface·Amrita MohantyMeena Lakhmipathy
Nov 13, 2010·Survey of Ophthalmology·Savitri SharmaSomasheila Murthy

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