Microstructure, morphology, and ultrafast dynamics of a novel edible microemulsion

Langmuir : the ACS Journal of Surfaces and Colloids
Ranajay SahaSamir Kumar Pal

Abstract

An edible microemulsion (ME) composed of Tween 80/butyl lactate/isopropyl myristate (IPM)/water has been formulated. Pseudoternary phase diagram of the system contains a large single isotropic region. The phase behavior of the system is also studied at low pH (2.6) and in 0.9% NaCl solution. Conductivity, viscosity, ultrasonic velocity, and compressibility studies find consistent results in the structural transition (from water-in-oil (w/o) to bicontinuous, and from bicontinuous to oil-in-water (o/w)) behavior of the ME. Dynamic light scattering studies reveal the size of the MEs. The absorption and steady state emission spectra of 4-(dicyanomethylene)-2-methyl-6-(p-dimethylamino-styryl)-4H-pyran (DCM) successfully probe the polarity of the ME at its solvation shell and shows the efficacy of hosting model drug molecules. The rotational anisotropy of the dye has been studied to ascertain the geometrical restriction of the probe molecule. Picosecond-resolved fluorescence spectroscopy applies well to study the relaxation dynamics of water in the solvation shell of the MEs. The study finds strong correlation in the relaxation dynamics of water with the structure of host assembly and offers an edible ME system which could act as a p...Continue Reading

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Citations

Mar 12, 2013·The Journal of Physical Chemistry. B·Chiranjib BanerjeeNilmoni Sarkar
Jan 15, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·Surajit RakshitSamir Kumar Pal
Dec 23, 2016·The Journal of Physical Chemistry. B·Muhammad Faizan NazarMuhammad Zubair
Sep 14, 2016·Drug Development and Industrial Pharmacy·F H Xavier-JuniorE S T Egito
Aug 16, 2018·Langmuir : the ACS Journal of Surfaces and Colloids·Muhammad Faizan NazarAzwan Mat Lazim

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