Microsurgical treatment of arteriovenous malformations: analysis and comparison with stereotactic radiosurgery

Journal of Neurosurgery
H J PikusR E Harbaugh

Abstract

To compare microsurgical and stereotactic radiosurgical treatment of arteriovenous malformations (AVMs), the authors analyzed a prospective series of 72 consecutive patients who were treated microsurgically for cerebral AVMs by one neurosurgeon. The authors then compared the results of microsurgical treatment with published results of stereotactic radiosurgical treatment of small AVMs. Patients were categorized by age, gender, presentation, and preoperative neurological status. The AVMs were categorized by size, location, presence of deep venous drainage, and Spetzler-Martin grade. Outcome was assessed for angiographic obliteration, hemorrhage following treatment, presence of a new, persistent postoperative neurological deficit, and Glasgow Outcome Scale (GOS) score. Ordinal logistic regression was used to model the GOS score and to predict new postoperative deficits. Generalized estimating equations were used to compare published results of microsurgical and stereotactic radiosurgical treatment of AVMs. Kaplan-Meier event-free survival plots were generated to compare the two modalities with respect to hemorrhage following treatment. Overall, six patients (8.3%) exhibited a new persistent neurological deficit postoperatively. S...Continue Reading

References

Mar 1, 1975·Lancet·B Jennett, M Bond
Jul 1, 1992·Journal of Neurosurgery·L SteinerM Steiner
Oct 1, 1991·Journal of Neurosurgery·L D LunsfordR J Coffey
Jul 12, 1990·The New England Journal of Medicine·R C Heros, K Korosue
Mar 1, 1988·Journal of Neurosurgery·R D BrownR J Maciunas
Oct 1, 1986·Journal of Neurosurgery·R F Spetzler, N A Martin
Oct 1, 1994·Neurosurgery·K S Harbaugh, R E Harbaugh
Jan 1, 1994·Neurosurgery·M G Hamilton, R F Spetzler
Nov 1, 1993·Journal of Neurosurgery·L SteinerM Steiner
Jun 1, 1996·Journal of Neurosurgery·W A FriedmanP S Kubilis

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Citations

Jul 8, 2010·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Douglas KondziolkaL Lunsford
Feb 4, 2005·Neurosurgical Review·Alexei L Krivoshapkin, Evstafy G Melidy
May 25, 2012·Current Atherosclerosis Reports·Brad E ZachariaE Sander Connolly
Mar 20, 2002·Current Neurology and Neuroscience Reports·Jodi L Smith, Bhuwan Garg
Oct 2, 2002·Current Treatment Options in Neurology·Glenn D. Graham
May 22, 2003·European Journal of Radiology·Michael SödermanGöran Edner
Mar 15, 2003·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·K GanapathySwatee Halbe
Aug 1, 2000·Clinical Privilege White Paper
Jun 11, 1999·The New England Journal of Medicine·UNKNOWN Arteriovenous Malformation Study Group
Jun 29, 2007·The New England Journal of Medicine·Robert M Friedlander
Nov 1, 2007·Journal of Spinal Disorders & Techniques·Yingpeng XiaYoshiaki Toyama
Feb 10, 2006·Neurosurgical Focus·J McInerneyR E Harbaugh
Jun 6, 2000·Journal of Neurosurgery·S MaesawaL D Lunsford
Oct 13, 2001·Journal of Neurosurgery·J Hillman
Jan 17, 2002·Journal of Neurosurgery·Bruce E Pollock, John C Flickinger
Sep 26, 2002·Journal of Neurosurgery·Deepak Agrawal
Oct 31, 2002·Journal of Neurosurgery·Roberto C Heros
Jan 7, 2004·Journal of Neurosurgery·Michael K MorganElizabeth Ritson
Apr 17, 2004·Journal of Neurosurgery·Bruce E PollockPaul D Brown
Sep 9, 2004·Journal of Neurosurgery·Bruce E Pollock, Fredric B Meyer
Dec 10, 2013·Current Treatment Options in Neurology·Bradley A Gross, Rose Du
Mar 13, 2014·Journal of Neurosurgery·Dale DingJason P Sheehan
Aug 12, 2014·Journal of Neurosurgery·Mohamed Samy Elhammady, Roberto C Heros
Aug 5, 2009·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Adam G BackPeter M Shedden
Feb 20, 2013·Acta neurochirurgica·Alberto FranzinPietro Mortini
Dec 26, 2015·World Neurosurgery·Wuyang YangJudy Huang
Nov 17, 2015·Expert Review of Neurotherapeutics·Michael CrimminsJared Knopman
Nov 12, 2014·TheScientificWorldJournal·Norman AjiboyeRodney Bell
May 23, 2012·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Bradley A Gross, Rose Du
Nov 24, 2011·Neurosurgery Clinics of North America·Alfred P SeeMichael Lim
Nov 1, 2011·Disease-a-month : DM·Hamad I Farhat
Jun 24, 2015·World Neurosurgery·Adam M H YoungE Jerome St George
Oct 13, 2000·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·M K MorganN Little
Oct 3, 2000·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·K NozakiH Kikuchi
Jan 1, 2015·Nature Reviews. Disease Primers·Michael T LawtonRobert F Spetzler

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