Microwave-assisted activation and modulator removal in zirconium MOFs for buffer-free CWA hydrolysis

Dalton Transactions : an International Journal of Inorganic Chemistry
Y KalinovskyyB A Blight

Abstract

A novel, facile and efficient method was developed for the activation of acetic acid modulated zirconium MOFs. The protocol involves briefly heating the material in water using microwave irradiation. MOF-808, DUT-84 and UiO-66 were all activated in this manner to remove the modulator and organic solvent from the framework post synthesis, with retention of MOF integrity post activation. The degree of activation was characterised by the use of TGA and NMR. The catalytic activity of the activated MOFs and their non-activated counterparts was investigated for chemical warfare agent (CWA) hydrolysis. Upon activation, an increase in the rate of hydrolysis was observed in the degradation of CWA simulant dimethyl 4-nitrophenyl phosphate (DMNP). MOF-808 and DUT-84 were also screened as catalysts for the hydrolysis of the V-series agent VM, with remarkable half-lives obtained for MOF-808 in the absence of any buffers. Currently employed MOF activation procedures involve the use of additional organic solvents post synthesis; we believe this method to be ideally efficacious for the organic desolvation of zirconium MOFs and removing modulator additives.

References

Sep 7, 2013·Chemical Communications : Chem Comm·Michael J KatzOmar K Farha
Mar 5, 2014·Journal of the American Chemical Society·Hiroyasu FurukawaOmar M Yaghi
Aug 27, 2014·Journal of the American Chemical Society·Juncong JiangWalter G Klemperer
Mar 17, 2015·Nature Materials·Joseph E MondlochOmar K Farha
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May 17, 2017·Journal of the American Chemical Society·Michelle H TeplenskyDavid Fairen-Jimenez

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Citations

Sep 22, 2020·Chemical Society Reviews·Xuan ZhangOmar K Farha
Jan 14, 2021·Chemical Society Reviews·George T WilliamsPhilip A Gale
Apr 6, 2020·Chemical Science·Ross S Forgan
Sep 5, 2019·ACS Applied Materials & Interfaces·Eun Ji LeeNak Cheon Jeong

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