Microwave-assisted digestion followed by parallel electromembrane extraction for trace level perchlorate detection in biological samples

Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
Hakimu NsubugaAhsan Mushir Shemsi

Abstract

A simple and parallel electromembrane extraction (pEME) method was developed and used to investigate trace perchlorate ion contamination in seafood. In this method, three different EME units were arranged simultaneously and connected parallel to a single DC power supply. In each unit, the ClO4(-) ions were electro-kinetically extracted from the microwave digested seafood homogenates into 100mM NaOH via a supported liquid membrane (1-Hexanol). Influential extraction parameters were carefully investigated. Under optimized conditions, good linearity with a coefficient of determination (R(2)) of 0.9949 over a concentration range of 1-125μg/g was obtained. The limit of detection (LOD) was 0.04μgg(-1). The methods intraday and inter day precision varied between 4.3-5.6% respectively. Mean recoveries were up to 107% (n=6, RSD=0.7-6.8%). This method was applied to different seafood samples to assess its feasibility for real applications and it exhibited an enhanced sample throughput compatible with both microwave and ion chromatography.

References

Feb 24, 2001·Journal of Chromatography. a·C S Eskilsson, E Björklund
Feb 1, 2006·Journal of Chromatography. a·Stig Pedersen-Bjergaard, Knut Einar Rasmussen
Sep 14, 2007·Journal of Chromatography. a·Astrid GjelstadStig Pedersen-Bjergaard
Aug 9, 2011·Journal of Chromatography. a·Chung-Hung ChanFabian Wai-Lee Kung
Oct 1, 2013·Journal of Chromatography. a·Hakimu Nsubuga, Chanbasha Basheer
May 23, 2014·Analytica Chimica Acta·Lars Erik Eng EibakAstrid Gjelstad

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Citations

Jun 6, 2020·The Analyst·Magnus Saed RestanStig Pedersen-Bjergaard
Feb 29, 2020·Analytica Chimica Acta·Magnus Saed RestanStig Pedersen-Bjergaard

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