Microwave-assisted organic synthesis and transformations using benign reaction media

Accounts of Chemical Research
Vivek Polshettiwar, Rajender S Varma

Abstract

A nonclassical heating technique using microwaves, termed "Bunsen burner of the 21st century", is rapidly becoming popular and is dramatically reducing reaction times. The significant outcomes of microwave (MW)-assisted green chemistry endeavors, which have resulted in the development of synthetic protocols for drugs and fine chemicals synthesis that are relatively more sustainable, are summarized. The use of emerging microwave-assisted chemistry techniques in conjunction with greener reaction media is dramatically reducing chemical waste and reaction times in several organic syntheses and chemical transformations. A brief historic account of our own experiences in developing MW-assisted organic transformations, which involve various benign alternatives, such as solid-supported reagents, and greener reaction media, namely, aqueous, ionic liquid, and solvent-free, for the synthesis of various heterocycles, coupling reactions, oxidation-reduction reactions, and some name reactions are described. Synthesis of Heterocycles. The synthetic chemistry community has been under increased pressure to produce, in an environmentally benign fashion, the myriad of heterocyclic systems required by society in a short span of time, and one of th...Continue Reading

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Citations

Apr 30, 2011·Accounts of Chemical Research·Mallikarjuna N NadagoudaRajender S Varma
Mar 16, 2011·Chemical Reviews·Vivek PolshettiwarJean-Marie Basset
Nov 30, 2011·Journal of Chemical Education·Thomas A ShellThomas F Guetzloff
Jan 9, 2010·Nature Protocols·Jayati BanerjeeSanku Mallik
Jul 24, 2008·Chemical Society Reviews·Vivek Polshettiwar, Rajender S Varma
Dec 3, 2008·Chemical Communications : Chem Comm·Vivek PolshettiwarRajender S Varma
Mar 26, 2009·Chemical Communications : Chem Comm·Vivek PolshettiwarRajender S Varma
Nov 14, 2013·Organic Preparations and Procedures International·Hao Lin, Dianqing Sun
Oct 19, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·René MirandaManuel Salmón
Oct 3, 2015·The Journal of Organic Chemistry·Pradip K MaityPaul R Hanson
Mar 30, 2016·Scientific Reports·Buchi Reddy VaddulaDalip Kumar
Apr 6, 2017·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Sambasivarao Kotha, Chandravathi Chakkapalli
Feb 12, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Laura RinaldiGiancarlo Cravotto
Apr 19, 2018·Organic & Biomolecular Chemistry·Richa MishraLokman H Choudhury
Jan 23, 2018·Journal of Drug Targeting·Carla Júnia SantosFrancisco Moura Filho
Dec 22, 2011·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Camilla Moretto dos ReisAurea Echevarria
Oct 23, 2010·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Gholamhassan ImanzadehYagoub Mansoori
Jan 17, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Silvia TabassoGiancarlo Cravotto
May 4, 2010·Advanced Materials·Tsukasa TorimotoSusumu Kuwabata
Mar 20, 2010·Organic & Biomolecular Chemistry·Tony SzuppaBernd Ondruschka
May 8, 2010·Organic & Biomolecular Chemistry·Noelia RubioEster Vázquez
May 8, 2010·Organic & Biomolecular Chemistry·Sonja VisentinGiancarlo Cravotto
Sep 17, 2010·Dalton Transactions : an International Journal of Inorganic Chemistry·Paweł J FigielArmando J L Pombeiro
May 11, 2012·Chemical Communications : Chem Comm·R B Nasir Baig, Rajender S Varma
Jan 1, 2012·Organic Preparations and Procedures International·Baskar NammalwarWilliam W Barrow
Apr 22, 2009·Molecular Diversity·C Oliver Kappe, Doris Dallinger

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