Mid-life predictors of late-life depressive symptoms; determining risk factors spanning two decades in the Women's Heathy Ageing Project

Women's Midlife Health
Katherine E CampbellLorraine Dennerstein

Abstract

Data available from longitudinal studies of adequate duration to explore midlife risk factors for late life higher depressive symptom scores in women is lacking. This study examines midlife (mean ages 50 years and 60 years) predictors of late life (mean age 70 years) depressive symptom scores to enrich our understanding of the role of changing risk factors across the lifespan. This investigation was an assessment of the long-term impact of lifestyle and health variables on depressive symptoms. Data were drawn from an epidemiological prospective study of women's healthy ageing spanning two decades. Variables included assessment of mood, demographics, physical health, smoking status, attitudes towards ageing and menopause, alcohol consumption and employment. Analysis was conducted to determine the set of strongest predictors assessed in 1992 (mean age 50 years) and in 2002 (mean age 60 years) in relation to higher CESD-SF scores measured in 2012 (mean aged 70 years (n = 249)). A cross-sectional analysis determining concurrent associations at mean age 70 years was also conducted. An increase in positive mood at 50 and 60 years was associated with a 0.3 (95% CI 0.1-0.5) and 0.4 (95%CI 0.1-0.8) point reduction in CESD score at 70 ye...Continue Reading

References

Jun 1, 1988·Journal of Personality and Social Psychology·D WatsonA Tellegen
Jun 1, 1983·Acta Psychiatrica Scandinavica·A S Zigmond, R P Snaith
Mar 1, 1981·Journal of Behavioral Medicine·A D KannerR S Lazarus
Nov 1, 1994·Maturitas·L DennersteinC Morse
Jun 1, 1997·Journal of Psychosomatic Obstetrics and Gynaecology·L DennersteinH Burger
Dec 1, 1999·The Journal of Nervous and Mental Disease·L DennersteinE Dudley
Feb 8, 2002·Journal of Psychosomatic Research·Ingvar BjellandDag Neckelmann
Apr 6, 2002·Psychological Science·Barbara L Fredrickson, Thomas Joiner
Nov 14, 2002·Journal of Abnormal Psychology·Karen L KaschIan H Gotlib
Dec 28, 2002·Archives of Women's Mental Health·L DennersteinJ Guthrie
Mar 14, 2003·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Dan G Blazer
Sep 10, 2004·Menopause : the Journal of the North American Menopause Society·Lorraine DennersteinVictor W Henderson
Apr 6, 2006·Archives of General Psychiatry·Ellen W FreemanDeborah B Nelson
Aug 2, 2007·Obstetrics and Gynecology·Ellen W FreemanLi Sheng
Dec 1, 2007·Climacteric : the Journal of the International Menopause Society·K K VescoH D Nelson
Feb 4, 2009·Menopause : the Journal of the North American Menopause Society·Ellen W FreemanHui Lin
Jun 10, 2010·Menopause : the Journal of the North American Menopause Society·Ellen W Freeman
Apr 13, 2011·Clinics·Clóvis Alexandrino-SilvaLaura Helena Andrade
Feb 18, 2012·Climacteric : the Journal of the International Menopause Society·Siobán D HarlowUNKNOWN STRAW+10 Collaborative Group
Sep 11, 2013·Journal of Abnormal Psychology·Kristin Naragon-GaineyTimothy A Brown
Jan 16, 2014·International Review of Psychiatry·Cassandra E I SzoekePatricia Desmond
Jan 23, 2014·Menopause : the Journal of the North American Menopause Society·Claudio N Soares
Jun 11, 2014·Medicine and Science in Sports and Exercise·Sheila A DuganBarbara Sternfeld
Jul 15, 2016·Psychological Bulletin·Gabriela Kattan Khazanov, Ayelet Meron Ruscio
Nov 20, 2016·The Lancet. Psychiatry·Christine Kuehner
Dec 11, 2017·Women's Midlife Health·Ellen Sullivan Mitchell, Nancy Fugate Woods

❮ Previous
Next ❯

Citations

Jan 1, 2021·Brain Sciences·Anna M CybulskaElżbieta Grochans

❮ Previous
Next ❯

Software Mentioned

Affectometer
SPSS ( Statistical Package for Social Science )
STATA15

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.