Mid-term outcomes in unbalanced complete atrioventricular septal defect: role of biventricular conversion from single-ventricle palliation

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Meena NathanPedro J Del Nido

Abstract

Management strategy for unbalanced complete atrioventricular septal defects (CASVSDs) includes single-ventricle (SV) palliation and primary or staged biventricular (BiV) repair. More recently, BiV conversion (BiVC) from SV palliation and staged BiV recruitment (BiVR) have also been advocated. This study assesses mid-term outcomes in patients with unbalanced CASVSDs according to management strategy. Consecutive patients with unbalanced CASVSDs who underwent surgery at a tertiary care centre from January 2000 to February 2016 with institutional review board approval. The index surgery was defined as the first palliation procedure for the SV group, a BiV repair for the BiV repair group and conversion or the first procedure for recruitment for the BiVC/BiVR group. Kaplan-Meier and Cox regression were used for time-to-event analysis of death/transplant and unplanned reinterventions that occurred after the index surgery. There were 212 patients: 82 (38.7%) had SV palliation, 67 (31.6%) had BiV repair and 63 (29.7%) had BiVC/BiVR, respectively; 50 patients had undergone a successful BiVC. There were 93 (43.9%) boys; 51 (24%) patients had Down syndrome; and 101 (48%) patients had heterotaxy. In the entire cohort, there were 40 (18.9%) ...Continue Reading

References

Oct 1, 1996·Journal of the American College of Cardiology·M S CohenJ Rychik
Apr 9, 2005·Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual·Meryl S Cohen, Thomas L Spray
Aug 4, 2005·The Journal of Thoracic and Cardiovascular Surgery·Nilto C De OliveiraGlen S Van Arsdell
Nov 27, 2007·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Eva Maria Delmo WalterFelix Berger
Feb 3, 2009·Pediatric Cardiology·Gabe E OwensSonal T Owens
Oct 13, 2009·The Journal of Thoracic and Cardiovascular Surgery·Sitaram M EmaniPedro J del Nido
Mar 10, 2010·The American Journal of Cardiology·Monesha Gupta-MalhotraJames H Moller
Dec 14, 2011·The Journal of Thoracic and Cardiovascular Surgery·John E FokerLee A Pyles
Oct 16, 2012·Journal of the American College of Cardiology·Sitaram M EmaniPedro J del Nido
Dec 26, 2012·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Andrea Z BeatonMary T Donofrio
Apr 9, 2013·Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual·David M OvermanDavid B Gremmels
Apr 9, 2013·Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual·Sitaram M Emani, Pedro J del Nido
Apr 23, 2013·The Annals of Thoracic Surgery·Meena NathanPedro J Del Nido
Apr 1, 2010·World Journal for Pediatric & Congenital Heart Surgery·David M OvermanChristian Pizarro
Jul 23, 2013·The Journal of Thoracic and Cardiovascular Surgery·John E FokerLee A Pyles

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Citations

Feb 13, 2019·Circulation Journal : Official Journal of the Japanese Circulation Society·Fengpu HeShoujun Li
Jan 25, 2018·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Meena NathanPedro J Del Nido
Aug 10, 2020·Current Cardiology Reports·Nicholas D AndersenJoseph W Turek
Jan 25, 2018·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Edward BurattoIgor E Konstantinov
Mar 31, 2021·Journal of Cardiac Surgery·Christopher GreenleafJorge D Salazar
May 20, 2021·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Benedikt MayrMasamichi Ono
Jun 3, 2021·Children·P Syamasundar Rao
May 18, 2021·Seminars in Thoracic and Cardiovascular Surgery·Jae Gun KwakSitaram M Emani
May 19, 2021·Seminars in Thoracic and Cardiovascular Surgery·Antonia SchulzIgor E Konstantinov
Jun 13, 2021·The Journal of Thoracic and Cardiovascular Surgery·Edward Buratto, Igor E Konstantinov

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