PMID: 9440805Jan 24, 1998Paper

Midazolam in treatment of various types of seizures in children

Brain & Development
C YakinciY Durmaz

Abstract

Midazolam is a recently developed water-soluble benzodiazepine that shares anxiolytic, muscle relaxant, hypnotic and anticonvulsant actions with other members of this class. There are limited studies that midazolam can be used successfully to treat seizures in adults and children. In this study, 0.2 mg/kg intramuscular (i.m.) midazolam was administered to 11 children (eight boys and three girls), aged 3 days to 4 years (mean age 1.8 +/- 1.4 years), with seizures of various types. In all but one child, seizures stopped in 15 s-5 min after injection. No side effects were observed. These results suggest that i.m. administration of midazolam may be useful in a variety of seizures during childhood, especially in case of intravenous (i.v.) line problem.

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Citations

Oct 3, 1999·Critical Care Medicine·J IgartuaM Sagy
Oct 24, 2000·Brain & Development·N O KutluY Durmaz
Jun 6, 2000·Brain & Development·H YoshikawaY Oda
May 28, 2003·Brain & Development·Nurettin Onur KutluHanifi Soylu
Jul 30, 2008·British Journal of Clinical Pharmacology·Simon N MuchohiCharles R J C Newton
Feb 24, 2001·Journal of Child Neurology·T FişginD Akgün
Dec 6, 2005·Clinical Pediatrics·Sahika BaysunY K Yavuz Gürer

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