Middle cerebral artery blood velocity, arterial diameter and muscle sympathetic nerve activity during post-exercise muscle ischaemia

Acta Physiologica Scandinavica
F PottNiels H Secher

Abstract

During exercise the transcranial Doppler determined mean blood velocity (Vmean) increases in the middle cerebral artery (MCA) and reflects cerebral flood flow when the diameter at the site of investigation remains constant. Sympathetic activation could induce MCA vasoconstriction and in turn elevate Vmean at an unchanged cerebral blood flow. In 12 volunteers we evaluated whether Vmean relates to muscle sympathetic nerve activity (MSNA) in the peroneal nerve during rhythmic handgrip and post-exercise muscle ischaemia (PEMI). The luminal diameter of the dorsalis pedis artery (AD) was taken to reflect the MSNA influence on a peripheral artery. Rhythmic handgrip increased heart rate (HR) from 74 +/- 20 to 92 +/- 21 beats min-1 and mean arterial pressure (MAP) from 87 +/- 7 to 105 +/- 9 mmHg (mean +/- SD; P < 0.05). During PEMI, HR returned to pre-exercise levels while MAP remained elevated (101 +/- 9 mmHg). During handgrip contralateral MCA Vmean increased from 65 +/- 10 to 75 +/- 13 cm s-1 and this was more than on the ipsilateral side (from 63 +/- 10 to 68 +/- 10 cm s-1; P < 0.05). On both sides of the brain Vmean returned to baseline during PEMI. MSNA did not increase significantly during handgrip (from 56 +/- 24 to 116 +/- 39 u...Continue Reading

Citations

Oct 4, 2011·Progress in Neurobiology·Thomas Seifert, Niels H Secher
Jan 6, 2006·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Mads K Dalsgaard
Nov 18, 2003·Clinical Physiology and Functional Imaging·D S KimmerlyJ K Shoemaker
Dec 14, 2011·Clinical Physiology and Functional Imaging·Lauro C ViannaAntonio Claudio Lucas da Nóbrega
Jul 28, 2010·Experimental Physiology·Thomas SeifertNiels H Secher
Oct 2, 2012·Experimental Physiology·Sushmita PurkayasthaPeter B Raven
Oct 6, 2009·Experimental Physiology·Christos K LykidisGeorge M Balanos
Nov 12, 2016·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·J VerbreeMjp van Osch
Dec 26, 2006·Journal of Dental Research·Y HasegawaT Nokubi
Oct 7, 2010·Journal of Dental Research·J SakagamiY Maeda
Sep 16, 2017·Cardiovascular Engineering and Technology·Hamed RezaieAfsaneh Mojra
Jun 23, 2015·The Journal of Head Trauma Rehabilitation·Mary ClausenJohn Leddy
Jul 8, 2000·Stroke; a Journal of Cerebral Circulation·J M SerradorR L Bondar
Oct 23, 2004·American Journal of Physiology. Heart and Circulatory Physiology·Shigehiko OgohNiels H Secher
Jul 11, 2007·Exercise and Sport Sciences Reviews·Lars Nybo, Peter Rasmussen
Jan 24, 2019·Sports Medicine·Steven J Trangmar, José González-Alonso
Aug 29, 2007·Sports Medicine·Jordan S Querido, A William Sheel
Feb 20, 2018·Journal of Physiological Anthropology·Erin D Ozturk, Can Ozan Tan
May 6, 2019·The Journal of Physiological Sciences : JPS·Keisho Katayama, Mitsuru Saito
Apr 1, 2014·The Journal of Physiological Sciences : JPS·Yuji YamaguchiNaoyuki Hayashi
Mar 21, 2007·American Journal of Physiology. Heart and Circulatory Physiology·Yu-Sok KimJohannes J van Lieshout
Dec 14, 2011·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Peter RasmussenJohannes J van Lieshout
May 8, 2000·Journal of Applied Physiology·F PottN H Secher
Feb 28, 2002·Anesthesia and Analgesia·Nicolas BruderFrançois Gouin
Jun 14, 2000·Journal of Applied Physiology·C A GillerM R Hatab
Oct 27, 2007·Journal of Applied Physiology·Neils H SecherJohannes J Van Lieshout
Apr 10, 2010·Journal of Applied Physiology·Shigehiko OgohTomoko Sadamoto
Feb 14, 2016·American Journal of Physiology. Heart and Circulatory Physiology·Eliza ProdelJames P Fisher
Jan 4, 2019·The Journal of Physiological Sciences : JPS·Shigehiko OgohTomoko Sadamoto

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.