Middle Ear Function and Pathophysiology in Andean Children Living at High Altitudes

High Altitude Medicine & Biology
S Allen CounterGöran Laurell

Abstract

Counter, S. Allen, Leo H. Buchanan, Fernando Ortega, Anthony B. Jacobs, and Göran Laurell. Middle ear function and pathophysiology in Andean children living at high altitudes. High Alt Med Biol. 18:163-170, 2017.-The extent of altitude-related middle ear disorders in children native to high altitudes is unclear. This study examined middle ear pathophysiology in two groups of children living in high-altitude Ecuadorian Andean communities by investigating middle ear pressure (MEP), tympanic membrane compliance (TMC), and ear canal volume (ECV) using tympanometry, and by otological examination. Altitude I Group lived at 2850 m, and Altitude II Group resided at around 4000 m. The two high-altitude groups were compared with a reference group of children residing at sea level. Mean MEP was -3.6 daPa (SD: 39.2), 3.5 daPa (SD: 28.7), and 1.3 daPa (SD: 13.6) for Altitude I Group, Altitude II Group, and the Sea Level Group, respectively. The MEP was not significantly different among the three groups. Mean TMC was 0.63 cm3(SD: 0.51), 0.60 cm3(SD: 0.43), and 0.60 cm3(SD: 0.24) for Altitude I Group, Altitude II Group, and the Sea Level Group, respectively. The TMC was not significantly different among the three groups. Mean ECV was 1.1 (SD:...Continue Reading

References

May 1, 1988·The Journal of Allergy and Clinical Immunology·C D Bluestone, W J Doyle
Jun 1, 1994·Hearing Research·L Urbani, M Lucertini
Feb 1, 1996·Ear and Hearing·J J Haapaniemi
May 14, 1999·Archives of Pediatrics & Adolescent Medicine·B J BuchananP R Fischer
Dec 4, 2003·Heart & Lung : the Journal of Critical Care·George W RodwayMark H Sanders
Apr 23, 2004·Archives of Disease in Childhood·M P Samuels
Jun 14, 2005·The Journal of Laryngology and Otology·S Mirza, H Richardson
Aug 3, 2005·High Altitude Medicine & Biology·Fabiola León-VelardeGustavo Zubieta-Calleja
Jun 25, 2009·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Cemal CingiGerhard Rettinger
Oct 29, 2010·Genome Biology·Laura B Scheinfeldt, Sarah A Tishkoff
Nov 18, 2010·The Journal of Laryngology and Otology·B K Prasad
Oct 30, 2012·American Journal of Respiratory and Critical Care Medicine·John B West
Jun 14, 2013·The New England Journal of Medicine·Peter Bärtsch, Erik R Swenson
Jun 26, 2013·High Altitude Medicine & Biology·S Allen CounterFernando Ortega
Jun 13, 2015·High Altitude Medicine & Biology·Tatum S Simonson
Feb 24, 2016·The Medical Clinics of North America·Nicholas J Johnson, Andrew M Luks
May 25, 2016·High Altitude Medicine & Biology·Francisco C Villafuerte, Noemí Corante
Nov 20, 2016·High Altitude Medicine & Biology·S Allen CounterGöran Laurell

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.