Middle Ear Viral Load Considerations in the COVID-19 Era: A Systematic Review.

Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Jeffrey LiawHuseyin Isildak

Abstract

To systematically review the available medical literature to investigate the viral load in the middle ear and mastoid cavity and the potential risk of exposure to airborne viruses during otologic surgery. PubMed, MEDLINE, and Cochrane databases. This review was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Protocol. Using the Boolean method and relevant search term combinations for terms "mastoid," "middle ear," "virus," "exposure" "COVID-19" "SARS-CoV-2." PubMed, MEDLINE, and Cochrane databases were queried. A total of 57 abstracts were identified and screened by two independent reviewers. Following inclusion and exclusion criteria, 18 studies were selected for the final analysis. Due to the heterogeneity of clinical data, a meta-analysis was not feasible. Rhinovirus, followed by respiratory syncytial virus are reported to be the most prevalent viruses in MEF samples but formal statistical analysis is precluded by the heterogeneity of the studies. Drilling was identified to have the highest risk for aerosol generation and therefore viral exposure during otologic Surgery. The medical literature has consistently demonstrated the presence of nucleic acids of respiratory viruses in...Continue Reading

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Citations

Jun 24, 2021·Journal of Medical Virology·Bengul DurmazMahmut Tayyar Kalcioglu

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Methods Mentioned

BETA
Cochlear implant
nucleic
PCR

Software Mentioned

Risk of Bias Assessment tool for Non - randomized Studies ( Ro...

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