Middle East respiratory syndrome coronavirus: a comprehensive review

Frontiers of Medicine
Mahmoud M ShehataGhazi Kayali

Abstract

The Middle East respiratory syndrome coronavirus was first identified in 2012 and has since then remained uncontrolled. Cases have been mostly reported in the Middle East, however travel-associated cases and outbreaks have also occurred. Nosocomial and zoonotic transmission of the virus appear to be the most important routes. The infection is severe and highly fatal thus necessitating rapid and efficacious interventions. Here, we performed a comprehensive review of published literature and summarized the epidemiology of the virus. In addition, we summarized the virological aspects of the infection and reviewed the animal models used as well as vaccination and antiviral tested against it.

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Citations

Oct 28, 2016·Reviews in Medical Virology·Naif Khalaf Alharbi
Jan 5, 2017·Emerging Microbes & Infections·Mohamed A AliGhazi Kayali
Feb 23, 2017·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Hae-Sung NamSeung Woo Kim
Feb 8, 2018·Respiration; International Review of Thoracic Diseases·Ioana D OlaruChristoph Lange
May 30, 2019·EcoHealth·Sophie ZhuSharon L Deem
Jul 20, 2017·Scientific Reports·Yingying CongFulvio Reggiori
Mar 15, 2019·Emerging Microbes & Infections·Ahmed KandeilGhazi Kayali
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Sep 27, 2019·Frontiers in Veterinary Science·Elena Massó SagüésJose Manuel Sánchez-Vizcaíno
Jan 1, 2018·Current Treatment Options in Infectious Diseases·Anucha Apisarnthanarak, David J Weber
Feb 6, 2021·Human Vaccines & Immunotherapeutics·Mihir BhattaMalay Kumar Saha
Nov 25, 2020·BMJ Nutrition, Prevention & Health·Emma Derbyshire, Joanne Delange
Jun 3, 2021·Micromachines·Ala'aldeen Al-HalhouliMahmoud Abu Abeeleh

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