Midkine exists in astrocytes in the early stage of cerebral infarction

Brain Research. Developmental Brain Research
S WangM Osame

Abstract

Midkine (MK), a heparin-binding neurotrophic factor, is expressed in the early stage of experimental cerebral infarction in the zone surrounding the infarct. Double immunostaining with anti-MK and anti-glial fibrillary acidic protein showed existence of MK in astrocytic cytoplasm on postoperative day 2. Immunoelectron microscopic analysis revealed the presence of MK in the swollen astrocytic processes on postoperative day 4.

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Citations

Jul 20, 2002·Journal of the Neurological Sciences·Manabu WadaKiyomitsu Oyanagi
Mar 12, 2004·Cancer Letters·Kenji Kadomatsu, Takashi Muramatsu
Apr 30, 2004·Journal of Neurotrauma·Harutoshi SakakimaShuji Izumo
Jun 26, 2012·Pathology International·Kazuma Sakamoto, Kenji Kadomatsu
Jul 29, 2008·Alcoholism, Clinical and Experimental Research·Traute Flatscher-Bader, Peter A Wilce
Jan 28, 2014·British Journal of Pharmacology·Yoshihiro YoshidaMasako Ikutomo
Nov 6, 2004·Brain Research. Developmental Brain Research·Harutoshi SakakimaTakashi Muramatsu
Jan 1, 2010·Cancers·Hirofumi Jono, Yukio Ando
Jul 18, 2002·The Journal of Biological Chemistry·Gerald E StoicaAnton Wellstein

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