Midline congenital anomalies: the estimated occurrence among American Indian and Alaska Native infants

Clinical Genetics
D A Coddington, J J Hisnanick

Abstract

While congenital anomalies have been identified as the second leading cause of infant mortality among American Indians and Alaska Natives, limited information exists concerning the morbidity of such malformations. This study was undertaken to address this concern. Using data from the national hospital discharge database of the Indian Health Service, for the years 1980-1988, morbidity rates of seven, relatively common and easily identifiable midline malformations among liveborn infants in this minority population were estimated. The seven congenital anomalies and the estimated rates per 10000 births were: neural tube defects 8.09; oral clefts 29.03; abdominal wall defects 2.99; tracheoesophageal fistula 1.86; conotruncal heart defects 5.90; rectal atresia 3.15; and diaphragmatic hernia 3.24. Seven cases (1.1%) had two midline defects reported.

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Citations

Jan 28, 2003·International Journal of Circumpolar Health·Laura ArbourRima Rozen
Apr 19, 2008·Language, Speech, and Hearing Services in Schools·Elise Davis-McFarland
May 23, 2003·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Marit J BootAdriana C Gittenberger-de Groot
Jan 11, 2008·Pediatric Cardiology·Jennifer L Kornosky, Hamisu M Salihu
Dec 1, 2007·Birth Defects Research. Part A, Clinical and Molecular Teratology·Samson Y GebreabJürgen Symanzik
Jun 30, 2004·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Kamile MarakogluFahrettin Goze

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