Abstract
To compare angiographic and pathologic effects (ie, occlusion, recanalization) after embolization with Hydrogel-coated coils (HydroCoils) and fibered coils in the renal and internal iliac arteries after 7 days and 1 and 4 months in an animal model. Twelve sheep had 1 internal iliac and 1 renal artery randomly embolized with HydroCoils or fibered coils. Renal and internal iliac arteries were embolized with detachable 0.018-inch coils and pushable 0.035-inch coils, respectively. All animals had control angiography performed at 7 days, and 1 and 4 months to assess recanalization before euthanasia. Recanalization and inflammation were evaluated via pathologic examination. At 1 month, 100% of arteries embolized with HydroCoils were occluded vs 50% of those embolized with fibered coils (P = .004). At 4 months, 80% of arteries embolized with HydroCoils were occluded vs 25% of those embolized with fibered coils (P = .01). Surface of vessel occlusion was significantly greater for iliac arteries (96.7% ± 8.9) than for renal arteries (94.2% ± 5.3; P = .0076). Surface of occlusion of the renal arteries (92.2% ± 5.1) was lower for fibered coils than for HydroCoils (96.8% ± 4.7; P = .0287). Surface percentage of thrombus was significantly lo...Continue Reading
References
May 6, 2006·Stroke; a Journal of Cerebral Circulation·Ron C GabaTim W Malisch
Jul 1, 2008·Journal of Vascular and Interventional Radiology : JVIR·Ashwin P NambiarKlaus D Hagspiel
Oct 28, 2008·Journal of Vascular and Interventional Radiology : JVIR·Alex LaurentAndrew L Lewis
Mar 31, 2009·Journal of Vascular and Interventional Radiology : JVIR·Siddharth A PadiaMark J Sands
Sep 19, 2009·European Radiology·Mark R McCoyMonika Killer
Jul 21, 2010·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·M H T ReingesF J Hans
Sep 23, 2010·AJR. American Journal of Roentgenology·Scott O Trerotola, Reed E Pyeritz
May 17, 2011·Lancet·Philip M WhiteUNKNOWN HELPS trial collaborators
Sep 29, 2011·Journal of Vascular and Interventional Radiology : JVIR·Marcelo GuimaraesGregory M Cruise
Mar 5, 2013·Cardiovascular and Interventional Radiology·Alicia LabordaMiguel A de Gregorio
Apr 16, 2013·Journal of Vascular and Interventional Radiology : JVIR·Geert MaleuxChris Verslype
Jul 3, 2013·Journal of Vascular and Interventional Radiology : JVIR·Taku YasumotoNoriyuki Tomiyama
Sep 24, 2014·AJR. American Journal of Roentgenology·Avinash MedsingeErnesto Santos
Nov 3, 2017·Cardiovascular and Interventional Radiology·Audrey FohlenJean-Pierre Pelage