PMID: 1200047Nov 15, 1975Paper

Midtrimester pregnancy termination by intramuscular injection of a 15-methyl analogue of prostaglandin F2 alpha

American Journal of Obstetrics and Gynecology
J Robins, L I Mann

Abstract

Fifty patients between 12 and 20 weeks' gestation were treated with prostaglandin 15 (S) 15-methyl F2 alpha by repeated intramuscular injection of 250 mug at intervals of not less than 2 hours in order to evaluate its efficacy as an abortifacient. A success rate of 96 per cent was achieved with a mean initiaation-abortion interval of 16.5 +/- S.E.M. 1.12 hours. There were no serious complications. The most common side effects were vomiting in 82 per cent and diarrhea in 66 percent of cases. The abortifacient activity was correlated with serial serum progesterone determinations and continuous intra-amniotic pressure recordings in selected cases.

References


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Citations

Feb 26, 2005·Annals of the New York Academy of Sciences·Amy G BrownJerome F Strauss
May 4, 2004·Journal of the Society for Gynecologic Investigation·Sam Mesiano
Jul 2, 2004·Obstetrics and Gynecology·Phillip G StubblefieldLynn Borgatta
Apr 5, 2019·Reproduction, Fertility, and Development·Marina IlicicJonathan W Paul
Feb 13, 2020·Reproductive Sciences·Marina IlicicJonathan W Paul
May 26, 2017·BioMed Research International·Marina IlicicJonathan W Paul
Jan 1, 1976·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Y IshikawaT Ogawa
Jan 1, 1982·The Journal of International Medical Research·K Bhalla, C R Jenkins

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