Mifepristone-induced early abortion and outcome of subsequent wanted pregnancy

American Journal of Epidemiology
Ai-Min ChenYi-Min Cheng

Abstract

Follow-up information on subsequent pregnancies after mifepristone (RU486)-induced abortion is scarce. The authors examined whether one mifepristone-induced first-trimester abortion affects the outcome of a subsequent wanted pregnancy. In a study conducted in 1998-2001 at antenatal clinics in Beijing, Chengdu, and Shanghai, China, the authors enrolled 4,925 women with no history of induced abortion, 4,931 women with one previous mifepristone-induced abortion, and 4,800 women with one previous surgical abortion and followed them through pregnancy and childbirth. The adjusted odds ratio for preterm delivery in women with one mifepristone abortion compared with women with no abortion was 0.77 (95% confidence interval: 0.61, 0.98). Although the mean birth weight of infants born to women with mifepristone abortion was 33 g (95% confidence interval: 17, 49) higher than that of infants born to women with no abortion, the frequencies of low birth weight and mean lengths of pregnancy were similar. There were no significant differences in risk of preterm delivery, frequency of low birth weight, or mean infant birth weight in the comparisons of women with previous mifepristone abortion and women with surgical abortion. This study suggests...Continue Reading

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Citations

Oct 28, 2010·Archives of Gynecology and Obstetrics·Hua LiaoWeiyue Zeng
Aug 19, 2007·The New England Journal of Medicine·Jasveer VirkJørn Olsen
Nov 4, 2008·Journal of Perinatal Medicine·Manfred VoigtVolker Briese
Sep 18, 2015·American Journal of Epidemiology·Samantha E ParkerMartha M Werler
May 12, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Norbert WinerPatrick Rozenberg
Mar 7, 2008·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Changping GanQing Liu
Nov 7, 2012·BJOG : an International Journal of Obstetrics and Gynaecology·J MännistöM Niinimäki
Apr 27, 2010·Paediatric and Perinatal Epidemiology·Mao-Hua MiaoWei Yuan
May 22, 2016·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Dustin CostescuMatthew Reeves
Aug 18, 2020·Obstetrics and Gynecology·UNKNOWN American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins—Gynecology, Society of Family Planning
Jul 1, 2010·Central European Journal of Public Health·Ferenc BánhidyAndrew E Czeizel

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