Abstract
Migraine is a well-established risk factor for ischemic stroke, but migraine is also related to other vascular diseases. This study aims to investigate the association between migraine and cerebrovascular atherosclerosis in patients with acute ischemic stroke. We retrieved data on patients with ischemic stroke from the DUST (Dutch Acute Stroke Study). Migraine history was assessed with a migraine screener and confirmed by telephone interview based on the ICHD criteria (International Classification of Headache Disorders). We assessed intra- and extracranial atherosclerotic changes and quantified intracranial internal carotid artery calcifications as measure of atherosclerotic burden on noncontrast computed tomography and computed tomographic angiography. We calculated risk ratios with adjustments for possible confounders with multivariable Poisson regression analyses. We included 656 patients, aged 18 to 99 years, of whom 53 had a history of migraine (29 with aura). Patients with migraine did not have more frequent atherosclerotic changes in intracranial (51% versus 74%; adjusted risk ratio, 0.82; 95% confidence interval, 0.64-1.05) or extracranial vessels (62% versus 79%; adjusted risk ratio, 0.93; 95% confidence interval, 0.77...Continue Reading
References
Aug 9, 2008·BMJ : British Medical Journal·Tobias KurthJulie E Buring
Aug 20, 2009·Cephalalgia : an International Journal of Headache·G E Tietjen
Feb 12, 2010·Neurology·M E BigalR B Lipton
May 25, 2010·The American Journal of Medicine·June T SpectorSaman Nazarian
Feb 27, 2014·BMC Neurology·Tom van SeetersUNKNOWN DUST investigators
Nov 11, 2016·European Neurology·Daphne van der WillikMarieke J H Wermer
Citations
Jun 22, 2018·CNS Drugs·Leda Marina PomesPaolo Martelletti
Nov 1, 2017·Stroke; a Journal of Cerebral Circulation·Tracy E Madsen, Seemant Chaturvedi
Nov 1, 2017·Stroke; a Journal of Cerebral Circulation·Hendrikus J A van Os, Marieke J H Wermer
Feb 14, 2018·Stroke; a Journal of Cerebral Circulation·Tracy E MadsenSeemant Chaturvedi
Apr 10, 2019·Cephalalgia : an International Journal of Headache·Ke-Xin WenMaryam Kavousi
Jun 25, 2019·The International Journal of Neuroscience·Yanqing DengXiaoli Li
Oct 23, 2019·Pharmacogenomics·Marina BorroGiovanna Gentile
Apr 5, 2019·Neurology·Gerrit L J OnderwaterUNKNOWN BBMRI Metabolomics Consortium
Mar 5, 2020·The International Journal of Neuroscience·Yi BaoSiqin Zhou
Apr 5, 2020·Headache·Gretchen E Tietjen, Emily F Maly
Mar 4, 2020·The Journal of Headache and Pain·Dawn C BuseRichard B Lipton
May 19, 2019·The Journal of Headache and Pain·Leda Marina PomesPaolo Martelletti
Jan 14, 2021·Cell Death & Disease·Zhou YangBo Yu
Mar 7, 2021·International Journal of Environmental Research and Public Health·Yung-Kai HuangYu-Chao Chang
May 8, 2021·Frontiers in Human Neuroscience·Claudia AltamuraGianluca Coppola
Jun 26, 2021·Journal of Neurology·Claudia AltamuraFabrizio Vernieri
Aug 28, 2021·BMJ Open·Chien-Hua ChenChia-Hung Kao
Nov 23, 2021·Frontiers in Neuroscience·Katie M LinstraMarieke J H Wermer