Migration and pathogenicity of CD8 T cells in central nervous system diseases

Médecine sciences : M/S
Guillaume Martin-BlondelRoland S Liblau

Abstract

The implication of CD8 T cells in infectious and inflammatory diseases of the central nervous system has received increasing attention. CD8 T cells are crucial players of the adaptive immune system against neurotropic infections, but can also trigger tissue damage. Here we review the molecular mechanisms used by CD8 T cells to migrate into the central nervous system, and describe diseases that imply CD8 T cell-mediated pathogenicity. We also suggest therapeutic strategies targeting this population.

References

Jun 28, 2002·Trends in Neurosciences·Harald NeumannHans Lassmann
Apr 12, 2005·Nature Immunology·Barbara MolonAntonella Viola
Mar 3, 2006·The New England Journal of Medicine·Chris H PolmanUNKNOWN AFFIRM Investigators
Dec 26, 2006·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Samantha JilekRenaud A Du Pasquier
Jun 15, 2007·European Journal of Immunology·James D BrienJanko Nikolich-Zugich
Jun 29, 2007·Cancer Immunology, Immunotherapy : CII·Janet W de BeukelaarPeter A Sillevis Smitt
Oct 31, 2008·Lancet·Alastair Compston, Alasdair Coles
Nov 11, 2009·Neurology·A MarzocchettiI J Koralnik
Jan 22, 2010·The New England Journal of Medicine·Ludwig KapposUNKNOWN FREEDOMS Study Group
Mar 26, 2010·The Lancet Infectious Diseases·Monika MüllerUNKNOWN IeDEA Southern and Central Africa
Mar 30, 2010·Médecine sciences : M/S·Guillaume Breton
Jul 28, 2010·Journal of Neurology, Neurosurgery, and Psychiatry·Guillaume Martin-BlondelBruno Marchou
Dec 7, 2010·Nature Reviews. Neurology·Bruce J BrewAvindra Nath
Apr 29, 2011·Médecine sciences : M/S·Marion C LanteriMichael P Busch
Nov 25, 2011·PLoS Pathogens·Grégoire ChevalierDaniel Gonzalez-Dunia
Apr 17, 2012·The Journal of Immunology : Official Journal of the American Association of Immunologists·Tanja ScheiklRoland S Liblau
Apr 28, 2012·Brain : a Journal of Neurology·Christian G BienJan Bauer
May 18, 2012·The New England Journal of Medicine·Gary BloomgrenCarmen Bozic
Aug 29, 2012·Trends in Immunology·Britta Engelhardt, Richard M Ransohoff
Nov 24, 2012·Neurology·Caroline AntoniolRenaud A Du Pasquier
Aug 13, 2013·Neurology·Guillaume Martin-BlondelRoland S Liblau
Dec 21, 2013·Médecine sciences : M/S·Céline LouapreCatherine Lubetzki
Jan 17, 2014·Acta Neuropathologica·Gijs KooijHelga E de Vries
Jan 31, 2014·The New England Journal of Medicine·Paul S GiacominiUNKNOWN Maraviroc in Multiple Sclerosis–Associated PML–IRIS (MIMSAPI) Group
Feb 7, 2015·Médecine sciences : M/S·Lisa A Chakrabarti, Olivier Lortholary

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.

Related Papers

A.M.A. Archives of Neurology and Psychiatry
A A FEDINEC, H A MATZKE
Comptes rendus des séances de la Société de biologie et de ses filiales
O FOUSSARD-BLANPIN, J BRETAUDEAU
Resenha clínico-científica
A B FORTES
© 2021 Meta ULC. All rights reserved