Migration and risk of HIV acquisition in Rakai, Uganda: a population-based cohort study.

The Lancet. HIV
Oluwasolape OlaworeM Kate Grabowski

Abstract

In sub-Saharan Africa, migrants typically have higher HIV prevalence than non-migrants; however, whether HIV acquisition typically precedes or follows migration is unknown. We aimed to investigate the risk of HIV after migration in Rakai District, Uganda. In a prospective population-based cohort of HIV-negative participants aged 15-49 years in Rakai, Uganda, between April 6, 1999, and Jan 30, 2015, we assessed the association between migration and HIV acquisition. Individuals were classified as recent in-migrants (≤2 years in community), non-recent in-migrants (>2 years in community), or permanent residents with no migration history. The primary outcome was incident HIV infection. We used Poisson regression to estimate incidence rate ratios (IRRs) of HIV associated with residence status with adjustment for demographics, sexual behaviours, and time. Data were also stratified and analysed within three periods (1999-2004, 2005-11, and 2011-15) in relation to the introduction of combination HIV prevention (CHP; pre-CHP, early CHP, and late CHP). Among 26 995 HIV-negative people who participated in the Rakai Community Cohort Study survey, 15 187 (56%) contributed one or more follow-up visits (89 292 person-years of follow-up) and we...Continue Reading

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Citations

Feb 23, 2019·Health Education & Behavior : the Official Publication of the Society for Public Health Education·Philip KreniskeJohn S Santelli
Feb 23, 2020·Nature Communications·Mary Kate GrabowskiRonald H Gray
Jul 22, 2018·Journal of the International AIDS Society·Carol S CamlinJanet Seeley
Jul 22, 2018·Journal of the International AIDS Society·Susan CasselsJanet Seeley
Jan 31, 2020·Frontiers in Public Health·Tonya N TaylorSabina Hirshfield
Jan 13, 2019·International Journal of Behavioral Medicine·Jane LeeYuanjin Zhou
Feb 3, 2021·Journal of Medical Internet Research·Philip KreniskeJohn S Santelli
Aug 18, 2021·Global Public Health·Nicole Herpai On Behalf Of The Dynamics Study Team
Aug 7, 2021·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Jennifer E BrophyMary K Grabowski

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Methods Mentioned

BETA
circumcision
ELISA
PCR

Software Mentioned

R
STATA

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