Migration of Deformable Vesicles Induced by Ionic Stimuli

Langmuir : the ACS Journal of Surfaces and Colloids
Atsuji KodamaMiglena I Angelova

Abstract

We have investigated the dynamics of phospholipid vesicles composed of 1,2-dioleoyl- sn-glycero-3-phosphocholine triggered by ionic stimuli using electrolytes such as CaCl2, NaCl, and NaOH. The ionic stimuli induce two characteristic vesicle dynamics, deformation due to the ion binding to the lipids in the outer leaflet of the vesicle and migration due to the concentration gradient of ions, that is, diffusiophoresis or the interfacial energy gradient mechanism. We examined the deformation pathway for each electrolyte as a function of time and analyzed it based on the surface dissociation model and the area difference elasticity model, which reveals the change of the cross-sectional area of the phospholipid by the ion binding. The metal ions such as Ca2+ and Na+ encourage inward budding deformation by decreasing the cross-sectional area of a lipid, whereas the hydroxide ion (OH-) encourages outward budding deformation by increasing the cross-sectional area of a lipid. When we microinjected these electrolytes toward the vesicles, a strong coupling between the deformation and the migration of the vesicle was observed for CaCl2 and NaOH, whereas for NaCl, the coupling was very weak. This difference probably originates from the bind...Continue Reading

References

Jun 1, 1986·Chemistry and Physics of Lipids·D W Deamer, J Bramhall
Jan 1, 1986·Annals of the New York Academy of Sciences·J L Anderson
Dec 30, 1987·European Journal of Biochemistry·S A Tatulian
Feb 1, 1969·Journal of Cellular Physiology·J P Reeves, R M Dowben
Apr 1, 1981·Biophysical Journal·E BoroskeW Helfrich
Oct 1, 1993·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·V HeinrichB Zeks
Jun 1, 1994·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·L MiaoH G Döbereiner
Aug 29, 2003·Biophysical Journal·Rainer A BöckmannHelmut Grubmüller
Jan 16, 2008·The Journal of Physical Chemistry. B·Arnau CordomíJuan J Perez
Mar 29, 2008·European Biophysics Journal : EBJ·Jeremy PencerJohn Katsaras
Aug 12, 2008·Biophysical Journal·Nada KhalifatMiglena I Angelova
Mar 5, 2009·Physical Review Letters·J-B FournierM I Angelova
Mar 18, 2009·The Journal of Physical Chemistry. a·Robert VáchaPavel Jungwirth
Dec 25, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Takaaki MiuraAkihisa Shioi
Dec 1, 2010·Langmuir : the ACS Journal of Surfaces and Colloids·Benjamin KlasczykRumiana Dimova
Dec 21, 2011·Physical Review Letters·Yuka Sakuma, Masayuki Imai
Apr 14, 2012·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Takashi IgarashiKenji Katayama
Feb 18, 2016·Soft Matter·Atsuji KodamaMiglena I Angelova
May 14, 2016·Soft Matter·Darrell VelegolManish Kumar
Jan 13, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·James KruczekSagar A Pandit
Jun 2, 2017·Physical Chemistry Chemical Physics : PCCP·Z T GraberT Baumgart
Sep 13, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Atsuji KodamaMiglena I Angelova
Sep 15, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Baharan Ali DoostiTatsiana Lobovkina

❮ Previous
Next ❯

Citations

Mar 21, 2019·Soft Matter·Yunlong HanTongfei Shi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.