Migration of polyethylene wear debris in hip arthroplasties: a canine model

Journal of Applied Biomaterials : an Official Journal of the Society for Biomaterials
W J KraemerJ F Zhao

Abstract

The distal migration of polyethylene wear debris appears to be a major cause of loosening and osteolysis of cementless total hip arthroplasties. The use of modern cementing techniques, circumferential porous or hydroxyapatite (HA) coating has been advocated as a means of preventing access of the particles to the bone-implant interface. The purpose of this study was to compare the ability of different methods of implant fixation to prevent wear debris migration. Three each of smooth, porous-coated, HA-coated, and cemented hemiarthroplasties were implanted in the right hip of 12 dogs. Polyethylene particles were injected into the hip once a month for 4 months and then the femurs were sectioned. The percentage bone ingrowth was 8% for the smooth, 38% for the porous, and 83% for the HA-coated sections. Infiltration of the interface membrane by histiocytes containing polyethylene particles, and endosteal scalloping or osteolysis were found on all sections of the smooth prostheses. No particles or osteolysis were found on any sections of the other three types of prostheses. Capsular and lymph node sections from all dogs revealed histiocytic infiltration with numerous polyethylene particles present. It is concluded that the use of cem...Continue Reading

References

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Citations

Feb 24, 2009·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Hélène LiboubanDaniel Chappard
Mar 26, 2011·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Shang-You YangPaul H Wooley
Mar 25, 2014·Journal of Biomedical Materials Research. Part a·Kai ZhangPaul H Wooley
Jun 6, 2006·Acta Orthopaedica·Mikael SundfeldtChristina Gretzer
May 27, 2017·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Meghan M MoranDale Rick Sumner
Apr 3, 2003·Clinical Orthopaedics and Related Research·Jörgen AstrandPer Aspenberg
Jan 23, 2004·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·P MassinB Duponchel
Jan 6, 2001·Acta Orthopaedica Scandinavica·O RahbekK Søballe
Sep 25, 2004·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Bryan A WarmeR Lane Smith
Jul 29, 2005·The Journal of Bone and Joint Surgery. British Volume·S P TrikhaA J Edge
Dec 31, 2009·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Pieter J EmansRudolph G T Geesink
Apr 9, 2002·Clinical Orthopaedics and Related Research·Rudolph G T Geesink
Jul 27, 2017·Annals of Biomedical Engineering·Fernando Y Zapata-CornelioRuth K Wilcox
Sep 22, 2021·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·Renée HuggardGordon Corfield

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