Migration of the nucleus pulposus within the intervertebral disc during flexion and extension of the spine

Spine
A J FennellD W Hukins

Abstract

Magnetic resonance images were obtained of the lumbar spines of three volunteers in neutral, flexed, and extended postures. To measure migration of the nucleus pulposus within the intervertebral disc during flexion and extension of the spine in living people. Results of experiments on bisected cadaveric spines have indicated that the nucleus migrates posteriorly during flexion and anteriorly during extension in nondegenerate discs. Degenerate discs may have faults or fissures that result in abnormal motion of the nucleus. Proton density weighted, sagittal, magnetic resonance images were obtained from the lumbar spines of three volunteers. Measurements of the positions of the anterior and posterior margins of the nucleus and of flexion and extension angles were made on tracings of the images corresponding to neutral, flexed, and extended postures. The observed frequency (22 of 24 measurements) at which the margins of the nucleus migrated in the directions predicted by results of cadaveric studies was significantly greater than the frequency that would be expected by chance (P < 0.001). The two exceptions may be a result of disc degeneration. There was a significant (P < 0.05) linear correlation between the migration of the anter...Continue Reading

References

Nov 1, 1994·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·V RascheW Schepper

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Citations

Jan 20, 2006·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Monica Millisdotter, Björn Strömqvist
Nov 14, 2008·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Fackson MwaleJohn Antoniou
Mar 6, 2010·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Peter J FazeyKevin P Singer
May 11, 2005·Journal of Manipulative and Physiological Therapeutics·Ralph E GayRoni L Evans
Jun 14, 2005·The Orthopedic Clinics of North America·Rudolf BertagnoliSandra Voigt
Mar 8, 2005·The Spine Journal : Official Journal of the North American Spine Society·Tyson A C BeachJack P Callaghan
Jul 27, 2001·Clinical Biomechanics·J R MeakinD W Hukins
Nov 1, 2003·The Spine Journal : Official Journal of the North American Spine Society·F Todd Wetzel, Ronald Donelson
Feb 21, 2014·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Kelly R WadeNeil D Broom
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Oct 22, 2011·Clinical Biomechanics·Jalil NazariRichard A Graveling
Feb 5, 2011·Physical Medicine and Rehabilitation Clinics of North America·Ronald Donelson
Oct 6, 2005·Spine·Anthony TsantrizosThomas Steffen
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Dec 2, 1999·Clinical Radiology·S Morgan, A Saifuddin
Feb 1, 2006·Clinical Biomechanics·Peter J FazeyKevin P Singer
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Jul 1, 2020·Journal of Biomechanical Engineering·Ruspi Maria Luisa, Cristofolini Luca

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