Mild and Practical Dirhodium(II)/NHPI-Mediated Allylic and Benzylic Oxidations with Air as the Oxidant

Chemistry : a European Journal
Yi WangYuanhua Wang

Abstract

Aerobic allylic and benzylic oxidations catalyzed by dirhodium(II) complexes with N-hydroxyphthalimide (NHPI) are described. The open flask reaction occurs at mild temperature, using air as the oxidant. Mechanistic studies suggest that dirhodium(II) complexes axially coordinate with NHPI to activate the O-H bond in NHPI and decrease the bond-dissociation energy (BDE).

References

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Apr 14, 2017·The Journal of Organic Chemistry·Yi WangYuanhua Wang

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