Mild Dirhodium(II)-Catalyzed Chemo- and Regioselective Azidation of Arenes

Organic Letters
Yi WangYuanhua Wang

Abstract

A mild chemo- and regioselective aromatic azidation reaction catalyzed by a dirhodium(II) catalyst with Zhdankin's reagent as the azide source is described. A variety of functional groups were well tolerated under the reaction conditions. Mechanistic studies suggested that the Rh2(II,II)-bound azide intermediate, rather than the free azide radical, is the key active species in the reaction.

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Citations

Feb 12, 2020·Chemistry : a European Journal·Yi WangYuanhua Wang

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