PMID: 6370618May 1, 1984Paper

Military antishock trouser (MAST). Application as a reversible fluid challenge in patients on high PEEP

M S Jastremski, K M Beney


Fluid management in the critically ill patient receiving high levels of positive end-expiratory pressure (PEEP) can be difficult. PEEP may cause the cardiac index to fall due to a decrease in left ventricular preload. However, the high intrathoracic pressures produced by PEEP negate the usefulness of the pulmonary artery occlusion pressure (PAo) as a measurement of left ventricular preload. The military antishock trouser (MAST), which has been presumed to compress the venous capacitance reservoir and auto-transfuse 500 to 1,000 ml to the central circulation, was used as a reversible predictor of the effects of fluids on 12 critically ill patients receiving PEEP greater than 10 cm H2O with a decreased cardiac index. Hemodynamic variables were measured before, during, and after MAST inflation. Fluids were given in a quantity sufficient to maintain the same PAo after MAST deflation as achieved with the initial inflation. A significant improvement of cardiac performance and a high correlation between MAST and post-MAST variables was observed. Application of MAST as a reversible fluid challenge is a useful method for predicting optimal fluid management.


Sep 1, 1977·The Journal of Trauma·N E McSwain
Nov 25, 1982·The New England Journal of Medicine·I M WeismanR M Rogers
Feb 1, 1980·Critical Care Medicine·M Walkinshaw, W C Shoemaker
Feb 12, 1981·The New England Journal of Medicine·F JardinJ P Bourdarias
Nov 1, 1981·The Journal of Trauma·F A GaffneyC G Blomqvist
Jan 1, 1981·The Journal of Trauma·B A PalafoxA B Gazzaniga


May 1, 1988·Annals of Emergency Medicine·N E McSwain

Related Concepts

Care of Intensive Care Unit Patient
Anti-Shock Trousers
Positive End-Expiratory Pressure
Respiratory Distress Syndrome, Adult

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Lipidomics & Rhinovirus Infection

Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Torsion Dystonia

Torsion dystonia is a movement disorder characterized by loss of control of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. Here is the latest research.

Archaeal RNA Polymerase

Archaeal RNA polymerases are most similar to eukaryotic RNA polymerase II but require the support of only two archaeal general transcription factors, TBP (TATA-box binding protein) and TFB (archaeal homologue of the eukaryotic general transcription factor TFIIB) to initiate basal transcription. Here is the latest research on archaeal RNA polymerases.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.