Millisecond-timescale local network coding in the rat primary somatosensory cortex

PloS One
Seif Eldawlatly, Karim Oweiss

Abstract

Correlation among neocortical neurons is thought to play an indispensable role in mediating sensory processing of external stimuli. The role of temporal precision in this correlation has been hypothesized to enhance information flow along sensory pathways. Its role in mediating the integration of information at the output of these pathways, however, remains poorly understood. Here, we examined spike timing correlation between simultaneously recorded layer V neurons within and across columns of the primary somatosensory cortex of anesthetized rats during unilateral whisker stimulation. We used bayesian statistics and information theory to quantify the causal influence between the recorded cells with millisecond precision. For each stimulated whisker, we inferred stable, whisker-specific, dynamic bayesian networks over many repeated trials, with network similarity of 83.3±6% within whisker, compared to only 50.3±18% across whiskers. These networks further provided information about whisker identity that was approximately 6 times higher than what was provided by the latency to first spike and 13 times higher than what was provided by the spike count of individual neurons examined separately. Furthermore, prediction of individual n...Continue Reading

References

Jan 1, 1992·Experimental Brain Research·D J SimonsD P Bryant
Jun 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·B E MercierM Glickstein
Jan 1, 1995·Experimental Brain Research·R Izraeli, L L Porter
Jul 30, 1999·Cerebral Cortex·A A Ghazanfar, M A Nicolelis
Jun 10, 2000·Journal of Neurophysiology·J S Nettleton, W J Spain
Sep 1, 2000·Respiration Physiology·B G LindseyR Shannon
Feb 24, 2001·Cerebral Cortex·G MirabellaM E Diamond
Apr 3, 2001·Nature Reviews. Neuroscience·F VarelaJ Martinerie
Oct 5, 2001·Nature Reviews. Neuroscience·A K EngelW Singer
Nov 16, 2001·Neuron·R S PetersenM E Diamond
Mar 12, 2002·The European Journal of Neuroscience·Irina A ErchovaMathew E Diamond
Jul 26, 2002·Current Opinion in Neurobiology·R S PetersenMathew E Diamond
Aug 14, 2002·Irish Journal of Medical Science·J Murphy, K D Cashman
Feb 21, 2003·AORN Journal·Doreen Wagner
Feb 21, 1997·Journal of Insect Physiology·M Burrows, P L. Newland
Aug 2, 2003·Nature·Kenneth D HarrisGyörgy Buzsáki
Apr 2, 2004·Journal of Neurophysiology·Mengliang Zhang, Kevin D Alloway
Apr 6, 2004·Nature Neuroscience·Tansu CelikelDaniel E Feldman
Aug 20, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Guglielmo FoffaniK A Moxon
Feb 5, 2005·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·Ed J WraithDoug A Brooks
Mar 18, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·W Bryan Wilent, Diego Contreras
Apr 30, 2005·Nature Reviews. Neuroscience·Kenneth D Harris
Jul 21, 2005·BMC Neuroscience·J ChiuO V Favorov
Jul 14, 2006·Current Opinion in Neurobiology·David KleinfeldMathew E Diamond
Sep 8, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Ehsan ArabzadehMathew E Diamond
Oct 13, 2006·Journal of Neurophysiology·S B SimonsM Tommerdahl
Nov 24, 2006·PLoS Computational Biology·V Anne SmithErich D Jarvis
Feb 24, 2007·The Journal of Physiology·Christiaan P J de KockBert Sakmann
May 23, 2007·Nature Neuroscience·Christoph KapferMassimo Scanziani
May 13, 1983·Science·S KirkpatrickM P Vecchi
Sep 28, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Janaina PantojaM A Nicolelis
Oct 30, 2007·Neuron·Carl C H Petersen
Jun 3, 2008·Nature Neuroscience·Shigeyoshi FujisawaGyörgy Buzsáki
Jul 25, 2008·Nature·Jonathan W PillowEero P Simoncelli
Oct 31, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Simona TemereancaD J Simons
Feb 21, 2009·Nature Reviews. Neuroscience·Rodrigo Quian Quiroga, S Panzeri
May 5, 2009·Neuron·Bilal Haider, David A McCormick
May 8, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Guglielmo FoffaniJ Aguilar

Citations

Nov 22, 2011·Journal of Neuroscience Methods·Ki Yong KwonKarim Oweiss
Nov 19, 2013·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Mehdi AghagolzadehKarim Oweiss
Aug 24, 2011·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Jianbo LiuKarim Oweiss
Jun 15, 2021·Brain Informatics·Eslam MounierSeif Eldawlatly

Methods Mentioned

BETA
PCA

Related Concepts

Related Feeds

Barrel cortex

Here is the latest research on barrel cortex, a region of somatosensory and motor corticies in the brain, which are used by animals that rely on whiskers for world exploration.

Related Papers

Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Juan AcerosArto V Nurmikko
© 2021 Meta ULC. All rights reserved