Mimics and chameleons of optic neuritis

Practical Neurology
Dinushi Weerasinghe, Christian Lueck

Abstract

Optic neuritis is a common problem and most neurologists are familiar with it. Recent studies have suggested that it can be overdiagnosed in as many as 10% of cases. The major reasons for this relate to confusion regarding terminology and lack of familiarity with common mimics. This article covers typical 'idiopathic' demyelinating optic neuropathy (IDON) and several possible variations in the way it can present (chameleons). We then discuss several conditions that can mimic IDON, including neuromyelitis optica, sarcoidosis, chronic relapsing inflammatory optic neuropathy, anterior ischaemic optic neuropathy, infectious/parainfectious optic neuropathy, neuroretinitis, Leber's hereditary optic neuropathy, and some 'ocular' mimics including autoimmune retinopathy and central serous choroidoretinopathy.

References

May 1, 1984·Archives of Ophthalmology·L M JampolH Gilbert
Feb 1, 1995·Neurology·M RodriguezL T Kurland
Jun 1, 1993·Archives of Ophthalmology·R W Beck, P A Cleary
May 1, 1996·American Journal of Ophthalmology·J D TrobeP A Cleary
May 1, 1997·American Journal of Ophthalmology·J B MizenerR H Kardon
Apr 21, 1999·QJM : Monthly Journal of the Association of Physicians·J P ZajicekD Mitchell
Sep 27, 2001·Archives of Ophthalmology·V PurvinD M Jacobson
Nov 29, 2001·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·J L KeltnerP T Yip
Jul 3, 2002·Ophthalmology·Robert C Watzke, William T Shults
Nov 21, 2002·Current Opinion in Ophthalmology·Rod ForoozanRobert C Sergott
Dec 21, 2002·Lancet·S J HickmanG T Plant
Jan 23, 2003·Brain : a Journal of Neurology·D KiddE M Graham
Sep 25, 2003·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Larry P FrohmanLeonard Bielory
Sep 28, 2005·Japanese Journal of Ophthalmology·Toshihiko MatsuoIchiro Yamadori
Mar 24, 2006·The New England Journal of Medicine·Laura J Balcer
Apr 12, 2006·Archives of Ophthalmology·Nicole E GrossRuth Sigal
Jun 20, 2007·Seminars in Neurology·Edward J AtkinsNancy J Newman
Jul 31, 2007·Acta Ophthalmologica·Maria WangMichael Larsen
Apr 15, 2008·Seminars in Immunopathology·John R Heckenlively, Henry A Ferreyra
Oct 6, 2009·Journal of the Neurological Sciences·Jacqueline Palace
Dec 19, 2009·Journal of Neurology, Neurosurgery, and Psychiatry·A PetzoldG T Plant
Jan 13, 2010·The Neurologist·Vitaly TerushkinStephen Prystowsky
May 18, 2010·Survey of Ophthalmology·J Alexander FraserNancy J Newman
Nov 9, 2010·Survey of Ophthalmology·Dinelli M Monson, Justine R Smith
Nov 26, 2010·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Steven L Galetta, Wayne T Cornblath
Feb 15, 2011·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Valerie PurvinAki Kawasaki
May 24, 2011·Handbook of Clinical Neurology·Edward J AtkinsValerie Biousse
Jul 14, 2012·Clinical & Experimental Ophthalmology·Godfrey QuinSamantha Fraser-Bell
Jul 14, 2012·Clinical & Experimental Ophthalmology·Gerald LiewSamantha Fraser-Bell
Jul 28, 2012·Middle East African Journal of Ophthalmology·Adel H AlsuhaibaniFahad B Al Badr
Jan 3, 2013·Clinical & Experimental Ophthalmology·Matthew J ThurtellG Michael Halmagyi
Mar 15, 2013·Practical Neurology·Sui Hsien WongG T Plant
Apr 3, 2013·Progress in Retinal and Eye Research·Marc H LevinA S Verkman
May 24, 2013·Journal of Neurology·Axel Petzold, Gordon T Plant
Jul 19, 2013·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Alex P LangeAnthony L Traboulsee
Aug 3, 2013·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Tsui-Kang HsuJorn-Hon Liu
Oct 26, 2013·Journal of Neurology·Henrik HorwitzJette Lautrup Frederiksen
Dec 18, 2013·Lancet Neurology·Ahmed T ToosyDavid H Miller
Jan 16, 2014·Autoimmunity Reviews·Axel Petzold, Gordon T Plant
Feb 4, 2014·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Young-Min LimKwang-Kuk Kim

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Citations

Jan 11, 2018·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Bruna Garbugio DutraAntônio Carlos Martins Maia
Jan 11, 2017·Neurology·Michael J BradshawTanuja Chitnis
Mar 29, 2019·Current Opinion in Rheumatology·Andrew R Romeo, Benjamin M Segal
Oct 20, 2018·Neurology and Clinical Neuroscience·Tatsuhiko SanoShuzo Shintani
Jun 18, 2020·Practical Neurology·Siew Mei YapDaniel G Healy
May 30, 2017·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Mari Kathrine SandØystein Kalsnes Jørstad
Jun 18, 2020·Practical Neurology·Christian J Lueck
Sep 17, 2020·Clinical Neurology and Neurosurgery·Tomoaki ShimaAkira Tsujino
Jan 8, 2021·Multiple Sclerosis and Related Disorders·Joana Costa Novo, Helena Felgueiras
Feb 4, 2021·Journal of Pediatric Neurosciences·Aditya V NairVivek Mathew
Jul 3, 2020·Multiple Sclerosis and Related Disorders·José Miguel AlvesJoana Guimarães
May 26, 2021·BMJ Case Reports·Isaac G Freedman, Anita A Kohli
Jul 6, 2021·European Journal of Ophthalmology·Jean-Baptiste DucloyerPierre Lebranchu
Sep 2, 2021·Curēus·Moayad M AlqurashiAbdullah Bukhari
Dec 16, 2020·Neurology·Alberto VogrigJérôme Honnorat

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