Mindfulness and pharmacological prophylaxis have comparable effect on biomarkers of inflammation and clinical indexes in chronic migraine with medication overuse: results at 12 months after withdrawal

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Licia GrazziEmanuela Sansone

Abstract

Chronic migraine (CM) is a disabling condition arising from a complex mixture of interconnected biological, psychological and social factors, and is often associated with medication overuse (MO). Mindfulness is emerging as a helpful treatment for pain, and one study showed that the longitudinal 12 months' course of CM-MO patients that attended mindfulness-based treatment alone was similar to that of patients receiving medical prophylaxis alone; in this study, we describe the course of biomarkers of inflammation. Our results provide initial evidence of sustained similar effects on reduced concentration of biomarkers of inflammation, although not sizeable enough to reach statistical significance. Whether more intensive treatment and/or larger samples would lead to greater changes is unknown, but these encouraging preliminary findings suggest further research is warranted.

References

Sep 4, 2009·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Licia GrazziGennaro Bussone
Sep 4, 2009·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·F AndrasikG Bussone
Nov 11, 2010·Current Pain and Headache Reports·Aubrey N ManackRichard B Lipton
Jun 19, 2013·Cephalalgia : an International Journal of Headache·UNKNOWN Headache Classification Committee of the International Headache Society (IHS)
Jul 16, 2013·Headache·Paul Durham, Spyros Papapetropoulos
Jul 22, 2014·Headache·Rebecca Erwin WellsElizabeth Loder
Oct 5, 2014·Cephalalgia : an International Journal of Headache·Gretchen E Tietjen, Jagdish Khubchandani
Nov 25, 2014·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Fengzhi WangGuofeng Tai

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Citations

Jan 13, 2018·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Ilaria Di Donato, Antonio Federico
Aug 20, 2019·Expert Review of Neurotherapeutics·Noemi FaeddaVincenzo Guidetti
Sep 1, 2017·Expert Review of Neurotherapeutics·Abouch V Krymchantowski, Carla da Cunha Jevoux
May 31, 2020·Current Pain and Headache Reports·Daniel G RogersTodd A Smitherman
May 29, 2018·Headache·Alberto RaggiDomenico D'Amico
Aug 1, 2019·Arquivos de neuro-psiquiatria·Fernando KowacsMauro Eduardo Jurno
Jan 15, 2020·Expert Review of Neurotherapeutics·Rebecca Erwin WellsZev Schuman-Olivier
Nov 11, 2020·Headache·Ashley N PolkTodd A Smitherman
Jul 3, 2021·Expert Review of Neurotherapeutics·Karen Santos FerreiraAna Miriam Velly

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