Mindfulness instruction for HIV-infected youth: a randomized controlled trial

Lindsey WebbErica M S Sibinga


HIV-infected youth experience many stressors, including stress related to their illness, which can negatively impact their mental and physical health. Therefore, there is a significant need to identify potentially effective interventions to improve stress management, coping, and self-regulation. The object of the study was to assess the effect of a mindfulness-based stress reduction (MBSR) program compared to an active control group on psychological symptoms and HIV disease management in youth utilizing a randomized controlled trial. Seventy-two HIV-infected adolescents, ages 14-22 (mean age 18.71 years), were enrolled from two urban clinics and randomized to MBSR or an active control. Data were collected on mindfulness, stress, self-regulation, psychological symptoms, medication adherence, and cognitive flexibility at baseline, post-program, and 3-month follow-up. CD4+ T lymphocyte and HIV viral load (HIV VL) counts were also pulled from medical records. HIV-infected youth in the MBSR group reported higher levels of mindfulness (P = .03), problem-solving coping (P = .03), and life satisfaction (P = .047), and lower aggression (P = .002) than those in the control group at the 3-month follow-up. At post-program, MBSR participant...Continue Reading

Associated Clinical Trials


Nov 25, 2003·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·F Patrick RobinsonLinda Witek-Janusek
Jul 17, 2004·Journal of Psychosomatic Research·Paul GrossmanHarald Walach
Feb 13, 2007·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Shamini JainGary E R Schwartz
Jun 6, 2007·Journal of Abnormal Child Psychology·John R Z AbelaRandy P Auerbach
Oct 11, 2007·JAMA : the Journal of the American Medical Association·Sheldon CohenGregory E Miller
Nov 22, 2007·Journal of Holistic Nursing : Official Journal of the American Holistic Nurses' Association·Lynn S Koerbel, Donna M Zucker
Jan 16, 2008·Explore : the Journal of Science and Healing·Erica M S SibingaJonathan M Ellen
May 12, 2010·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Carolyn Y FangSteven D Douglas
Feb 26, 2011·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Erica M S SibingaJonathan M Ellen
Sep 20, 2011·Journal of Pain and Symptom Management·Larissa G DuncanMallory O Johnson
Oct 5, 2011·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Katherine AndrinopoulosUNKNOWN Adolescent Medicine Trials Network for HIV/AIDS Interventions
Mar 13, 2012·AIDS and Behavior·Ann Bartley WilliamsJulie A Womack
Jan 1, 2011·North American Journal of Medical Sciences·Asfandyar Khan Niazi, Shaharyar Khan Niazi
Jan 8, 2014·JAMA Internal Medicine·Madhav GoyalJennifer A Haythornthwaite
Apr 29, 2014·Explore : the Journal of Science and Healing·Erica M S SibingaJonathan M Ellen

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