Mindfulness meditation and the immune system: a systematic review of randomized controlled trials

Annals of the New York Academy of Sciences
David S Black, George M Slavich

Abstract

Mindfulness meditation represents a mental training framework for cultivating the state of mindful awareness in daily life. Recently, there has been a surge of interest in how mindfulness meditation improves human health and well-being. Although studies have shown that mindfulness meditation can improve self-reported measures of disease symptomatology, the effect that mindfulness meditation has on biological mechanisms underlying human aging and disease is less clear. To address this issue, we conducted the first comprehensive review of randomized controlled trials examining the effects of mindfulness meditation on immune system parameters, with a specific focus on five outcomes: (1) circulating and stimulated inflammatory proteins, (2) cellular transcription factors and gene expression, (3) immune cell count, (4) immune cell aging, and (5) antibody response. This analysis revealed substantial heterogeneity across studies with respect to patient population, study design, and assay procedures. The findings suggest possible effects of mindfulness meditation on specific markers of inflammation, cell-mediated immunity, and biological aging, but these results are tentative and require further replication. On the basis of this analys...Continue Reading

References

Apr 18, 1991·Nature·E H Blackburn
Jun 15, 1997·Annals of Internal Medicine·J W MellorsC R Rinaldo
Sep 6, 2002·Biochemical Pharmacology·Alok C Bharti, Bharat B Aggarwal
Feb 13, 2003·Proceedings of the National Academy of Sciences of the United States of America·Angelika BierhausPeter P Nawroth
Jul 29, 2003·Psychosomatic Medicine·Richard J DavidsonJohn F Sheridan
Nov 25, 2003·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·F Patrick RobinsonLinda Witek-Janusek
Jul 17, 2004·Journal of Psychosomatic Research·Paul GrossmanHarald Walach
Oct 7, 2004·The Lancet Oncology·Edna Maria Vissoci ReicheHelena Kaminami Morimoto
Sep 2, 2006·The American Journal of Psychiatry·Thaddeus W W PaceChristine M Heim
May 1, 2008·Expert Review of Vaccines·Rajesh Kumar, Edith A Burns
Aug 27, 2009·Pediatrics·David S BlackSteve Sussman
Sep 9, 2009·Annals of the New York Academy of Sciences·Lobsang Rapgay, Alexander Bystrisky
Sep 24, 2009·JAMA : the Journal of the American Medical Association·Michael S KrasnerTimothy E Quill
Mar 31, 2010·Journal of Consulting and Clinical Psychology·Stefan G HofmannDiana Oh
Oct 12, 2010·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Barry S OkenAlexandra Amen
Nov 3, 2010·Psychoneuroendocrinology·Tonya L JacobsClifford D Saron
Dec 18, 2010·Science·Jennifer Couzin-Frankel
May 3, 2011·The Annals of Thoracic Surgery·Michel E van GenderenJasper van Bommel
Aug 6, 2011·Nature Reviews. Immunology·Michael R Irwin, Steven W Cole
Nov 16, 2011·Biological Research for Nursing·Cecile A LengacherThomas W Klein
Dec 6, 2011·Behaviour Research and Therapy·Donal G MacCoonAntoine Lutz
Mar 20, 2012·American Journal of Respiratory and Critical Care Medicine·Bartolome R CelliUNKNOWN ECLIPSE Investigators
Mar 24, 2012·Journal of Holistic Nursing : Official Journal of the American Holistic Nurses' Association·Cecile A LengacherMelissa Molinari Shelton
May 9, 2012·Preventive Medicine·Earl S FordSimon Capewell
Jul 11, 2012·Annals of Family Medicine·Bruce BarrettChristopher L Coe
Oct 20, 2012·Brain, Behavior, and Immunity·William B MalarkeyMaryanna Klatt
Oct 25, 2012·Brain, Behavior, and Immunity·Melissa A RosenkranzAntoine Lutz
Feb 8, 2013·Diabetes Care·Linda HaasUNKNOWN 2012 Standards Revision Task Force
Apr 23, 2013·Brain, Behavior, and Immunity·Elizabeth A HogeNaomi M Simon
May 3, 2013·Clinical Psychological Science : a Journal of the Association for Psychological Science·Michael L M MurphyGregory E Miller
Jun 26, 2013·Clinical Psychology Review·Bassam KhouryStefan G Hofmann
Jul 16, 2013·Clinical Psychological Science : a Journal of the Association for Psychological Science·George M Slavich, Steven W Cole
Jan 8, 2014·JAMA Internal Medicine·Madhav GoyalJennifer A Haythornthwaite

❮ Previous
Next ❯

Citations

Jun 2, 2016·Experimental Neurology·Vasiliki MichopoulosGretchen Neigh
Oct 1, 2016·Annual Review of Psychology·J David Creswell
Jan 18, 2017·MMW Fortschritte der Medizin·Martin OffenbächerJörg Schelling
Dec 5, 2017·Journal of the American Psychiatric Nurses Association·Linda Grabbe, Elaine Miller-Karas
May 3, 2018·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Ruth Q WoleverPoppy L A Schoenberg
Feb 13, 2018·Journal of Behavioral Medicine·R I FalkenbergM L Peters
Feb 27, 2019·Psychosomatic Medicine·J David CreswellBrian Chin
May 28, 2019·Nursing·Sandra Bernstein
Jun 9, 2019·International Journal of Molecular Sciences·William H Walker, Jeremy C Borniger
Apr 13, 2019·Stress and Health : Journal of the International Society for the Investigation of Stress·Jasmin E GuevaraChristopher P Fagundes
Sep 5, 2019·International Journal of Environmental Research and Public Health·Dorthe DjernisMia O'Toole
Nov 2, 2018·The Indian Journal of Medical Research·Santosh S GuptaMangesh Ghodke
Jan 25, 2019·European Psychiatry : the Journal of the Association of European Psychiatrists·Suhaer Zeki Al-FadhelMichael Maes
Jan 24, 2020·Aging & Mental Health·Tomás Caycho-RodríguezIsabel Cabrera-Orosco
Nov 5, 2019·Minerva anestesiologica·Luciana Boavista Barros HeilPatricia Rieken Macedo Rocco
Mar 15, 2020·Journal of Evaluation in Clinical Practice·Maria G Alessi, Jeanette M Bennett
May 14, 2020·Journal of Psychosomatic Obstetrics and Gynaecology·Serena MennittoDeborah Da Costa
Jun 25, 2020·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·William BushellPaul J Mills
Jan 7, 2020·Psychology & Health·Nicola S SchutteShian-Ling Keng
Jul 1, 2020·Clinical Trials : Journal of the Society for Clinical Trials·Julie Loebach WetherellUNKNOWN MEDEX Research Group
Sep 5, 2017·Clinical Psychology : a Publication of the Division of Clinical Psychology of the American Psychological Association·Archana BasuKarestan C Koenen
Aug 22, 2018·Journal of Experimental Neuroscience·Diana I Lurie
May 21, 2019·European Journal of Physical and Rehabilitation Medicine·Cristina BravoDaniel Catalan-Matamoros
Jul 28, 2020·Frontiers in Medicine·Leônidas Oliveira NetoKenio Costa Lima
Aug 28, 2020·Frontiers in Psychology·Sabrina VendittiMichele Zampieri
May 22, 2020·Personality Neuroscience·Satish JaiswalWei-Kuang Liang
Oct 21, 2016·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Andrea Danese, Stephanie J Lewis
Nov 10, 2017·Journal of Health Care Chaplaincy·David FleenorHeidi Swarts

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Advances in Mind-body Medicine
Jeffrey D Rediger, Lauren Summers
The Journal of the Arkansas Medical Society
Laura L Sisterhen
© 2022 Meta ULC. All rights reserved