Mineral nutrition of Streptomyces kanamyceticus for kanamycin formation.

Antimicrobial Agents and Chemotherapy
K Basak, S K Majumdar

Abstract

Kanamycin production by Streptomyces kanamyceticus ATCC 12853 requires magnesium sulfate and potassium phosphate at concentrations of 0.4 and 1.0 g per liter, respectively. The optimal concentrations of Fe and Zn for production of kanamycin are 0.25 and 0.575 mug/ml, respectively, whereas Mo at 0.04 mug/ml allows maximal cellular growth and antibiotic synthesis. Mn and Ca are without any effect. Cu, Co, Ni, and V have inhibitory effect on growth of the organism as well as kanamycin formation.

References

Jul 1, 1973·Antimicrobial Agents and Chemotherapy·K Basak, S K Majumdar
Nov 1, 1952·Journal of General Microbiology·C DONALDR J SWABY
Jul 1, 1958·Applied Microbiology·E KATZA SIVAK
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Apr 1, 1960·Journal of Bacteriology·S K MAJUMDAR, S K BOSE
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May 1, 1948·Journal of Bacteriology·D M Reynolds, S A Waksman

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