Mineral trioxide aggregate-based sealer: analysis of tissue reactions to a new endodontic material

Journal of Endodontics
Roberta Kochenborger ScarparoFabiana Soares Grecca

Abstract

The aim of this study was to evaluate the subcutaneous connective tissue reaction to mineral trioxide aggregate (MTA)-based sealer (Endo CPM Sealer; CPM Sealer; EGEO SRL, Buenos Aires, Argentina), MTA, and an epoxy resin-based sealer (AH Plus; Dentsply HERO Indústria e Comércio Ltda, Petrópolis, RJ, Brazil). Polyethylene tubes containing the test materials and empty tubes (control group) were implanted in the subcutaneous tissue of 18 rats. After 7, 30, and 60 days, observations were made for cellular inflammatory components, fibrous condensation, and abscess formation. Comparisons between groups and periods of time were made using the Friedman test and the Kruskall-Wallis test. Lymphocytes and plasmacytes were more intensely observed in the reaction to AH Plus sealer after 30 days (p < 0.05). MTA and the Endo CPM Sealer presented a behavior similar to that of the control group throughout the whole experiment. The Endo CPM Sealer presented biological potential. Characteristics of the inflammatory reaction were equivalent to those produced by MTA.

Citations

Aug 4, 2012·Journal of Applied Oral Science : Revista FOB·João Eduardo Gomes-FilhoJosé Arlindo Otoboni Filho
Dec 14, 2011·Medicina oral, patología oral y cirugía bucal·Sepideh VosoughhosseiniSirvan Doosti
Mar 29, 2014·Journal of Endodontics·Matthew T CarpenterJames C McPherson
Apr 25, 2013·Journal of Endodontics·Cauana Oliva TavaresRoberta Kochenborger Scarparo
Jan 17, 2012·Journal of Endodontics·Eloísa AssmannFabiana Soares Grecca
Nov 22, 2011·Journal of Endodontics·Seok-Woo ChangKee-Yeon Kum
Jul 27, 2011·Journal of Endodontics·Santiago MassiJuliane Maria Guerreiro-Tanomaru
Sep 8, 2011·International Endodontic Journal·R D MorgentalP M P Kopper
Apr 19, 2012·Dental Traumatology : Official Publication of International Association for Dental Traumatology·Luciano Tavares Angelo CintraEloi Dezan-Junior
Mar 17, 2012·International Dental Journal·Zahed MohammadiSousan Shalavi
Jul 24, 2012·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Naiana Viana ViolaPaulo Sérgio Cerri
Nov 28, 2013·Australian Endodontic Journal : the Journal of the Australian Society of Endodontology Inc·Kee-Yeon KumSeok Woo Chang
Jun 19, 2015·Dental Traumatology : Official Publication of International Association for Dental Traumatology·Julia Mourão BragaAntonio Paulino Ribeiro Sobrinho
Dec 3, 2014·Journal of Endodontics·Hui-min ZhouMarkus Haapasalo
Apr 28, 2016·Journal of Applied Oral Science : Revista FOB·Paulo Leal MedeirosMarina Angélica Marciano
Nov 4, 2017·Materials·William N HaLaurence J Walsh
Dec 8, 2017·Brazilian Dental Journal·Katerine Jahnecke PilownicFernanda Geraldo Pappen
Mar 29, 2019·Journal of Oral Science·João M SantosAna C Santos
Jul 20, 2018·Clinical Oral Investigations·Alexander Pompermayer JardinePatrícia Maria Poli Kopper
Dec 17, 2018·Odontology·David DonnermeyerEdgar Schäfer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.