Minimal chronic inactive gastritis: indicator of pre-existing helicobacter pylori gastritis?

Pathology, Research and Practice
G OberhuberF Wrba

Abstract

Minimal chronic inactive gastritis is regularly observed in routine histopathology. Presently, it is not clear whether this type of gastritis should be regarded as a histopathological entity or a normal variant. The similarity to lesions observed after H.pylori eradication prompted us to look for an association between minimal chronic inactive gastritis and status post H.pylori eradication. In a prospective study of 110 consecutive patients undergoing upper gastrointestinal endoscopy, at least two mucosal biopsies were taken from the gastric antrum and body. Gastritis was classified according to the Sydney System. Antibodies to H.pylori were determined serologically by immunofluorescence test, ELISA, and complement binding reaction. A status post eradication of H.pylori was revealed by medical history and/or positive serology; H.pylori gastritis was found in 39.1%, reactive gastritis in 12.7%, and minimal chronic inactive gastritis in 29.1%. In 19.1% a combination of reactive/ minimal chronic gastritis was diagnosed according to morphology. Status post eradication was observed significantly more often in cases with minimal chronic inactive gastritis (43.8%) than in cases with reactive gastritis (7.1%, p < 0.004). Furthermore, p...Continue Reading

References

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Citations

Jun 27, 2003·The American Journal of Surgical Pathology·Thomas WündischChristian Thiede
Apr 14, 2006·Der Internist·M Vieth, M Stolte
Oct 30, 1998·Pathology, Research and Practice·G OberhuberM Stolte
Nov 8, 2014·Alimentary Pharmacology & Therapeutics·R M Genta, A Sonnenberg
Mar 24, 2006·American Journal of Epidemiology·Pertti AroLars Agréus
Apr 26, 2003·Virchows Archiv : an International Journal of Pathology·M ViethM Stolte
Sep 16, 2000·Acta medica Austriaca·G Oberhuber, A Haidenthaler

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