Minimal Clinically Important Difference of the Multidimensional Fatigue Symptom Inventory-Short Form (MFSI-SF) for Fatigue Worsening in Asian Breast Cancer Patients

Journal of Pain and Symptom Management
Alexandre ChanYan Xiang Gan

Abstract

The minimal clinically important difference (MCID) of the Multidimensional Fatigue Symptom Inventory-Short Form (MFSI-SF), a questionnaire that measures cancer-related fatigue, has not been established in patients with cancer. This study aims to determine the MCID of the MFSI-SF. Breast cancer patients completed the MFSI-SF and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC-QLQ-C30) before chemotherapy and at least three weeks later. The EORTC-QLQ-C30 fatigue scale (EORTC-FA) was used as an anchor, and a receiver operating characteristic (ROC) curve was also used to identify the optimal MCID cut-off for fatigue deterioration. A distribution-based approach used one-third of the SD, half of the SD, and one SEM of the total MFSI-SF score to determine the MCID. A total of 201 patients were analyzed. Change scores of the MFSI-SF and EORTC-FA were moderately correlated (r = 0.47, P < 0.001). The EORTC-FA-anchored MCID was 8.69 points (95% CI: 4.03-13.34). The MCID attained from the ROC curve method was 4.50 points (sensitivity: 68.8%; specificity: 64.1%). For the distribution-based approach, the MCIDs corresponding to one-third of the SD, half of the SD, and one SEM were 5....Continue Reading

References

Dec 1, 1989·Controlled Clinical Trials·R JaeschkeG H Guyatt
Jan 24, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·D OsobaJ Pater
Jul 4, 1998·Cancer Practice·K D SteinP B Jacobsen
May 17, 2000·Journal of Clinical Epidemiology·J A HustedD D Gladman
Jul 10, 2003·Journal of Pain and Symptom Management·Shirley S HwangBasil Kasimis
Jan 9, 2004·Journal of Pain and Symptom Management·Kevin D SteinChristina Thors
Apr 27, 2005·Evaluation & the Health Professions·Kathleen J Yost, David T Eton
Jul 27, 2005·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·N LuoS C Li
Jan 18, 2006·American Journal of Epidemiology·Neil J Perkins, Enrique F Schisterman
Apr 24, 2007·The Spine Journal : Official Journal of the North American Spine Society·Anne G CopayThomas C Schuler
Jan 22, 2008·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·David H HenryDavid Cella
Aug 6, 2008·Annals of Oncology : Official Journal of the European Society for Medical Oncology·O Minton, P Stone
Feb 18, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J MaringwaUNKNOWN EORTC PROBE Project and Brain Cancer Group
Mar 5, 2011·Physical Therapy·Ying-Chih WangJerome E Mioduski
May 3, 2011·Indian Pediatrics·Rajeev Kumar, Abhaya Indrayan
Aug 2, 2013·The Journal of Manual & Manipulative Therapy·Alexis WrightAlicia Emerson Kavchak
Aug 22, 2014·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Kristine A DonovanPaul B Jacobsen
Sep 6, 2014·Journal of the National Comprehensive Cancer Network : JNCCN·Andrew D ZelenetzUNKNOWN National comprehensive cancer network
Apr 15, 2015·Journal of the National Comprehensive Cancer Network : JNCCN·William J GradisharRashmi Kumar
Aug 19, 2015·Journal of the National Comprehensive Cancer Network : JNCCN·Ann M BergerUNKNOWN National comprehensive cancer network
Oct 3, 2015·BMJ Open·Bradley C JohnstonGihad Nesrallah
Jul 9, 2016·BMC Medical Research Methodology·Åsa NordinAnna Dencker

❮ Previous
Next ❯

Citations

Apr 12, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Fiona YeoAlexandre Chan
Oct 23, 2020·Arthritis Care & Research·Claudia Elera-FitzcarraldGraciela S Alarcón
Jan 5, 2021·Breast Cancer Research and Treatment·AnnaLynn M WilliamsMichelle C Janelsins
May 6, 2021·Palliative & Supportive Care·Shila Amarsheda, Anjali R Bhise

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.