Minimal number of gradient directions for robust measurement of spherical mean diffusion weighted signal

Magnetic Resonance Imaging
Hua LiHarry T Chugani

Abstract

Determination of the minimum number of gradient directions (Nmin) for robust measurement of spherical mean diffusion weighted signal (S¯). Computer simulations were employed to characterize the relative standard deviation (RSD) of the measured spherical mean signal as a function of the number of gradient directions (N). The effects of diffusion weighting b-value and signal-to-noise ratio (SNR) were investigated. Multi-shell high angular resolution Human Connectome Project diffusion data were analyzed to support the simulation results. RSD decreases with increasing N, and the minimum number of N needed for RSD ≤ 5% is referred to as Nmin. At high SNRs, Nmin increases with increasing b-value to achieve sufficient sampling. Simulations showed that Nmin is linearly dependent on the b-value. At low SNRs, Nmin increases with increasing b-value to reduce the noise. RSD can be estimated as σS¯N, where σ = 1/SNR is the noise level. The experimental results were in good agreement with the simulation results. The spherical mean signal can be measured accurately with a subset of gradient directions. As Nmin is affected by b-value and SNR, we recommend using 10 × b / b1 (b1 = 1 ms/μm2) uniformly distributed gradient directions for typical h...Continue Reading

References

May 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·A SzaferJ C Gore
Jan 1, 1994·Biophysical Journal·P J BasserD LeBihan
Dec 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·H Gudbjartsson, S Patz
Jan 1, 1997·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·G J StaniszR M Henkelman
Aug 10, 2000·Magnetic Resonance Imaging·N G PapadakisT Adrian Carpenter
Mar 9, 2004·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J Sijbers, A J den Dekker
Apr 6, 2004·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Derek K Jones
Sep 15, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Adam W Anderson
Dec 26, 2006·NeuroImage·Sune N JespersenDmitriy A Yablonskiy
May 29, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Yaniv AssafPeter J Basser
Jun 29, 2010·NeuroImage·Daniel C AlexanderTim B Dyrby
Jun 28, 2011·NeuroImage·Els FieremansJoseph A Helpern
Feb 13, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S N SotiropoulosC Lenglet
Apr 30, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Emmanuel CaruyerRachid Deriche
May 25, 2013·NeuroImage·Stamatios N SotiropoulosUNKNOWN WU-Minn HCP Consortium
Apr 8, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Xiaoyu JiangJunzhong Xu
May 15, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Enrico KadenDaniel C Alexander
Oct 4, 2015·NeuroImage·Jens H JensenJoseph A Helpern
Jun 11, 2016·NeuroImage·Enrico KadenDaniel C Alexander
Oct 26, 2016·NeuroImage·Marco ReisertValerij G Kiselev
Dec 19, 2016·Magnetic Resonance Imaging·Emilie T McKinnonJoseph A Helpern
Sep 19, 2017·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Fernando CalamanteAlan Connelly
Apr 17, 2018·NeuroImage·Emilie T McKinnonJens H Jensen

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