PMID: 9527182Apr 4, 1998Paper

Minimally diluted tepid blood cardioplegia

The Annals of Thoracic Surgery
N HayashidaS Aoyagi

Abstract

To evaluate the effects of minimally diluted tepid blood cardioplegia, a prospective, randomized study was undertaken. Thirty-seven patients undergoing isolated primary coronary artery bypass grafting were randomized to receive standard 4:1 diluted tepid blood cardioplegia (4:1 group, n = 18) or minimally diluted tepid blood cardioplegia (Mini group, n = 19). Cardioplegic solution was delivered in an intermittent antegrade fashion in both groups. Myocardial oxygen and lactate metabolism, release of the MB isoenzyme of creatine kinase and thiobarbituric acid reactive substances, and cardiac function were measured during and after the operation. Myocardial oxygen consumption was significantly greater and lactate release was significantly lower in the Mini group than in the 4:1 group during cardioplegia. Minimally diluted blood cardioplegia resulted in more prompt resumption of lactate extraction, lower levels of release of the myocardial-specific isoenzyme of creatine kinase and thiobarbituric acid reactive substances during reperfusion, and better postoperative left ventricular function compared with the standard 4:1 cardioplegia. Minimally diluted tepid blood cardioplegia may provide superior myocardial protection than the stan...Continue Reading

References

Jan 1, 1992·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·R W LandymoreJ Fris
Jun 1, 1991·Journal of Cardiac Surgery·S V LichtensteinT A Salerno
Jun 1, 1989·The Annals of Thoracic Surgery·P Menasché, A Piwnica
Sep 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·N HayashidaD A Mickle
Jan 1, 1995·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·T IsomuraK Ohishi
Feb 1, 1995·The Annals of Thoracic Surgery·A M CalafioreD Lapenna
Mar 1, 1995·The Annals of Thoracic Surgery·N HayashidaD A Mickle
Oct 1, 1994·The Annals of Thoracic Surgery·N HayashidaD A Mickle
Jun 1, 1994·The Annals of Thoracic Surgery·D LapennaF Cuccurullo
May 1, 1994·The Annals of Thoracic Surgery·R W LandymoreJ Fris
Jan 1, 1993·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·T B Ferguson
Oct 1, 1996·The Annals of Thoracic Surgery·P Menasché
Oct 1, 1996·The Annals of Thoracic Surgery·L TorraccaR Ferrari

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Citations

Mar 10, 2001·The Annals of Thoracic Surgery·H J PenttiläK J Peuhkurinen
Apr 16, 2003·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Tadashi IsomuraAtsushi Yuda
Apr 17, 2002·Circulation Journal : Official Journal of the Japanese Circulation Society·Nobuhiko HayashidaShigeaki Aoyagi
May 1, 2004·Circulation Journal : Official Journal of the Japanese Circulation Society·Yoshitaka HayashiHikaru Matsuda
May 7, 2005·International Heart Journal·Muharrem I BadakEmin A Alayunt
Jun 26, 2012·Nihon rinsho. Japanese journal of clinical medicine·Tadashi Isomura
Aug 7, 2013·The Annals of Thoracic Surgery·Yasuhiro KotaniChristopher A Caldarone
Mar 5, 2015·Interactive Cardiovascular and Thoracic Surgery·Tadashi IsomuraMinoru Yoshida
Jul 25, 2003·Asian Cardiovascular & Thoracic Annals·Teing Ee TanHugh S Paterson
Dec 17, 2010·World Journal of Cardiology·Yves Durandy
Apr 9, 2009·Interactive Cardiovascular and Thoracic Surgery·Turki B AlbackerKevin Lachapelle
Oct 13, 2020·Journal of Cardiac Surgery·Claire M OwenNicola King

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