Minimally disseminated disease and outcome in overt orbital retinoblastoma

Pediatric Blood & Cancer
Rosario AscheroGuillermo L Chantada

Abstract

In this retrospective study of patients with overt orbital retinoblastoma, we evaluated minimally disseminated disease (MDD) in bone marrow and cerebrospinal fluid (CSF) using CRX and/or GD2 synthase as markers. Ten patients were evaluated-five (50%) at diagnosis and five upon relapse. MDD was detected in four cases (one in the bone marrow, two in the CSF, and in one case in both sites). All patients received chemotherapy and four received orbital radiotherapy. Seven patients relapsed or progressed and all of them died. Three patients remain in complete remission. There was no apparent correlation between MDD and the outcome.

References

Jan 9, 2003·Medical and Pediatric Oncology·Guillermo ChantadaEnrique Schvartzman
Dec 17, 2005·Pediatric Blood & Cancer·Guillermo ChantadaJean-Michel Zucker
Apr 25, 2006·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Carlos A Leal-LealJorge Amador-Zarco
Jun 1, 2013·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Viviana E LaurentGuillermo L Chantada
Apr 1, 2011·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Mohammad J AliVijay A P Reddy
Nov 19, 2014·Acta Ophthalmologica·Ana Vanesa TorbidoniMaría Teresa G de Dávila
Mar 10, 2016·PloS One·Paula TaichPaula Schaiquevich
Jun 24, 2017·Indian Journal of Ophthalmology·Santosh G HonavarVijay Anand P Reddy

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