Minimally invasive biomarker studies in eosinophilic esophagitis: A systematic review

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Brittany T HinesEvan S Dellon

Abstract

Eosinophilic esophagitis (EoE) is a chronic, inflammatory disease of the esophagus that currently requires repeated endoscopic biopsies for diagnosis and monitoring because no reliable noninvasive markers have been identified. To identify promising minimally invasive EoE biomarkers and remaining gaps in biomarker validation. We performed a systematic review of EMBASE, Ovid MEDLINE, PubMed, and Web of Science from inception to June 6, 2017. Studies were included if patients met the 2007 consensus criteria for EoE diagnosis, a minimally invasive biomarker was assessed, and the study included at least 1 control for comparison. The search identified 2094 studies, with 234 reviewed at full-text level, and 49 included in the analysis (20 adult, 19 pediatric, 7 pediatric and adult, and 3 not stated). Most (26 of 49) were published after 2014. Thirty-five studies included healthy controls, 9 analyzed atopic controls, and 29 compared samples from patients with active and inactive EoE. Minimally invasive biomarkers were obtained from peripheral blood (n = 41 studies), sponge or string samples (n = 3), oral or throat swab secretions (n = 2), breath condensate (n = 2), stool (n = 2), and urine (n = 2). The most commonly reported biomarkers...Continue Reading

References

Jan 1, 1993·Digestive Diseases and Sciences·S E AttwoodJ B Jones
Oct 24, 2002·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Hiroshi FujiwaraYukihiko Saeki
Jul 27, 2005·Inflammatory Bowel Diseases·Alex StraumannHans-Uwe Simon
Oct 25, 2006·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Michael R KonikoffMarc E Rothenberg
Jun 27, 2007·Journal of Pediatric Gastroenterology and Nutrition·Jennifer Z BullockMarc E Rothenberg
Oct 9, 2007·Gastroenterology·Glenn T FurutaUNKNOWN First International Gastrointestinal Eosinophil Research Symposium (FIGERS) Subcommittees
Feb 2, 2008·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Elizabeth T SchaeferSandeep K Gupta
Oct 28, 2008·The Journal of Allergy and Clinical Immunology·Sébastien ConusHans-Uwe Simon
Jul 23, 2009·Annals of Internal Medicine·David MoherUNKNOWN PRISMA Group
Jul 20, 2010·Journal of Pediatric Gastroenterology and Nutrition·Anup J PatelKari Nadeau
Jul 20, 2010·Journal of Pediatric Gastroenterology and Nutrition·Judy FuentebellaKari Nadeau
Sep 8, 2010·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Jennifer J HuangKari C Nadeau
Jan 8, 2011·The Journal of Allergy and Clinical Immunology·Carine BlanchardMarc E Rothenberg
Apr 12, 2011·The Journal of Allergy and Clinical Immunology·Chris A LiacourasSeema S Aceves
Jun 23, 2011·Journal of Pediatric Gastroenterology and Nutrition·Tammie NguyenKari C Nadeau
Jun 23, 2011·Journal of Pediatric Gastroenterology and Nutrition·Girish SubbaraoSandeep K Gupta
Jun 26, 2012·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Miguel J LanzRuben Gonzalez-Vallina
Aug 28, 2012·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Neeti Bhardwaj, Gisoo Ghaffari
Dec 12, 2012·Journal of Gastroenterology·Ma Paz ZafraVictoria del Pozo
Jul 31, 2013·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·W S LexmondE Fiebiger
Oct 15, 2013·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S JyonouchiA Cianferoni
Nov 28, 2013·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Joaquín Rodríguez-SánchezJosé Olmedo-Camacho
Jun 8, 2014·Gastroenterology·Frederic ClaytonKathryn A Peterson
Jul 6, 2014·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·David A KatzkaRebecca C Fitzgerald
Sep 13, 2014·The Journal of Allergy and Clinical Immunology. in Practice·Diana ColsonChristophe Dupont
Oct 1, 2014·The American Journal of Gastroenterology·Elizabeth T JensenEvan S Dellon
Feb 25, 2015·MicroRNA·Deepali V SawantAlexander L Dent
Mar 18, 2015·The American Journal of Gastroenterology·Evan S DellonNicholas J Shaheen
Apr 15, 2015·Internal Medicine Journal·H L PhilpottP R Gibson
Jun 3, 2015·Microbiome·Alain J BenitezMei-Lun Wang
Oct 22, 2015·The New England Journal of Medicine·Glenn T Furuta, David A Katzka
Oct 29, 2015·Pediatric Pulmonology·Nadia L KruppRobert S Tepper
Jan 17, 2016·Gastrointestinal Endoscopy·Abhishek WattsSandeep K Gupta
Mar 28, 2016·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Kenji M CunnionKelly M Maples
May 1, 2016·The Journal of Allergy and Clinical Immunology·Benjamin L WrightEvan S Dellon
May 21, 2016·The Journal of Allergy and Clinical Immunology·David W MorrisPatricia C Fulkerson

❮ Previous
Next ❯

Citations

Feb 2, 2019·Current Treatment Options in Gastroenterology·Quan M Nhu, Fouad J Moawad
Jan 22, 2020·Pediatric Research·Sanjay KumarSandeep K Gupta
Jan 25, 2020·Annual Review of Pathology·Amy D KlionBruce S Bochner
Dec 28, 2019·Journal of Pediatric Gastroenterology and Nutrition·Robert D Baker, Susan S Baker
Dec 14, 2019·Journal of Pediatric Gastroenterology and Nutrition·Anna HendersonPatricia C Fulkerson
Feb 23, 2019·Expert Review of Gastroenterology & Hepatology·Ángel Arias, Alfredo J Lucendo
Dec 14, 2018·Frontiers in Immunology·Benjamin L WrightR Sharon Chinthrajah
Oct 27, 2018·Frontiers in Medicine·Elisa Gomez TorrijosJoan Bartra
Dec 3, 2020·Journal of Clinical Medicine·Katarzyna ZdanowiczUrszula Daniluk
May 5, 2021·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Sathisha Upparahalli VenkateshaiahAnil Mishra
Mar 23, 2021·Allergy·Anna E CamilleriOdelya E Pagovich
Jul 30, 2021·The Journal of Allergy and Clinical Immunology. in Practice·Derek K ChuBrian P Vickery
Oct 28, 2021·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Emily C McGowan, Seema S Aceves

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Related Papers

Current Opinion in Gastroenterology
Alex Straumann, Petr Hruz
Journal of Neurogastroenterology and Motility
Jung Ho LeeHyojin Park
Journal of Pediatric Gastroenterology and Nutrition
Tammie NguyenKari C Nadeau
© 2022 Meta ULC. All rights reserved