Minimally Invasive Microincision Vitrectomy Surgery with an Intraoperative Dexamethasone Implant for Refractory Diabetic Macular Edema

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
Dong Hoon LeeYoung Hee Yoon

Abstract

To evaluate the 1-year results of 25-gauge microincision vitrectomy surgery (MIVS25) combined with intraoperative dexamethasone (DEX) implant for persistent diabetic macular edema (DME). This study enrolled patients who had a history of DME for ≥12 months and underwent MIVS25 and DEX implant injection. Best corrected visual acuity (BCVA) and central retinal thickness (CRT) were assessed postoperatively. Eighteen eyes were included in the analysis. Preoperatively, logMAR BCVA was 0.90 and CRT was 594 µm on average. CRT decreased until the 3-month follow-up visit and tended to increase at 6 months, but stabilized at 12 months with additional treatments in five eyes at 5 months postoperatively. Statistically significant improvement in BCVA was noted 1 month after treatment and at each subsequent follow-up visit (p < 0.001). MIVS25 combined with DEX implant injection might be utilized as an effective and safe alternative treatment for intractable DME.

Citations

Apr 6, 2018·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Takayasu NunomeChikako Suto
Jul 19, 2019·Journal of Current Ophthalmology·Mohammadreza AkhlaghiMohsen Pourazizi
Feb 16, 2017·Drugs·Sanket U Shah, Raj K Maturi
Jun 10, 2021·Therapeutic Advances in Ophthalmology·Victor M VillegasTimothy G Murray

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