Minimally invasive radio-guided parathyroidectomy

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
D RubelloM R Pelizzo

Abstract

We reported here the data on minimally invasive radio-guided parathyroidectomy (MIRP) in a large group of 253 patients enrolled from the whole series of 355 consecutive patients affected by primary hyperparathyroidism (P-HPT) referred to our center. On the basis of preoperative imaging including Sestamibi scintigraphy and neck ultrasound (US), 263 patients (74% of the whole series) with evidence of a solitary parathyroid adenoma (PA) and a normal thyroid gland were addressed to MIRP and in 253 (96%) of them this minimally invasive neck exploration was successfully performed. The MIRP protocol developed in our center consisted of a very low 1 mCi Sestamibi injection in the operating room a few minutes before the start of intervention, thus minimizing the radiation exposure dose to the patient and personnel. No major intraoperative complication was recorded in patients treated by MIRP and only a transient hypocalcemia in 8.5% of cases. The mean duration time for MIRP was 35 min and the mean hospital stay 1.2 days. Local anesthesia was also performed in 62 patients, 54 of whom were elderly patients with concomitant invalidating diseases contraindicating general anesthesia. No HPT relapse was observed during subsequent follow-up. T...Continue Reading

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Citations

Feb 22, 2008·Langenbeck's Archives of Surgery·Antonio Sitges-SerraJoan J Sancho
May 1, 2007·Thyroid : Official Journal of the American Thyroid Association·Douglas Politz, James Norman
Dec 6, 2006·Ultrasound Quarterly·Aya KamayaR Brooke Jeffrey
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Mar 14, 2007·Cirugía española·Antonio Sitges-Serra
Jun 1, 2010·Otolaryngologic Clinics of North America·David Chien, Heather Jacene

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