Minimally invasive versus the conventional open surgical approach of a radical cholecystectomy for gallbladder cancer: a retrospective comparative study

HPB : the Official Journal of the International Hepato Pancreato Biliary Association
Anil K AgarwalPuja Sakhuja

Abstract

Laparoscopic surgery has traditionally been contraindicated for the management of gall bladder cancer (GBC). This study was undertaken to determine the safety and feasibility of a laparoscopic radical cholecystectomy (LRC) for GBC and compare it with an open radical cholecystectomy (ORC). Retrospective analysis of primary GBC patients (with limited liver infiltration) and incidental GBC (IGBC) patients (detected after a laparoscopic cholecystectomy) who underwent LRC between June 2011 and October 2013. Patients who fulfilled the study criteria and underwent ORC during the same period formed the control group. During the study period, 147 patients with GBC underwent a radical cholecystectomy. Of these, 24 patients (primary GBC- 20, IGBC - 4) who underwent a LRC formed the study group (Group A). Of the remaining 123 patients who underwent ORC, 46 matched patients formed the control group (Group B). The median operating time was higher in Group A (270 versus 240 mins, P = 0.021) and the median blood loss (ml) was lower (200 versus 275 ml, P = 0.034). The post-operative morbidity and mortality were similar (P = 1.0). The pathological stage of the tumour in Group A was T1b (n = 1), T2 (n = 11) and T3 (n = 8), respectively. The media...Continue Reading

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Citations

Mar 29, 2016·The Surgical Clinics of North America·Motaz Qadan, T Peter Kingham
Sep 30, 2015·Surgical Endoscopy·Senthilnathan PalanisamyPalanivelu Chinnusamy
Sep 9, 2016·South Asian Journal of Cancer·Nikhil Suresh GhadyalpatilSaklani Avanish
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Mar 10, 2018·World Journal of Surgery·César Muñoz CastroNicolás Jarufe Cassis
Jun 22, 2018·Surgical Endoscopy·Xabier de AretxabalaIvan Roa
Jan 18, 2018·Digestive Surgery·Ho-Seong HanRoberto I Troisi
Feb 26, 2019·Journal of Surgical Oncology·Mahesh GoelSagar Kurunkar
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Nov 26, 2016·Gastroenterology Research and Practice·Giuseppe ZimmittiEdoardo Rosso
Apr 20, 2020·Surgical Endoscopy·Yoonhyeong ByunJin-Young Jang
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